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Pharmaceutical Raw Materials #126167

FLURBIPROFEN

Supplied By UMA Brothers, India

SYNONYMS: 2-FLUORO-ALPHA-METHYL-(1, 1'-BIPHENYL)-4-ACETIC ACID

CAS NO: 51543-40-9, MOLECULAR FORMULA: C15H13FO2, MOLECULAR WEIGHT: 244.26

IT IS IN POWDER FORM WITH MELTING RANGE: 110°C TO 111°C. IT IS AVAILABLE AS FLURBIPROFEN SODIUM AND FLURBIPROFEN AXETIL.

STANDARD: OFFERED OF PHARMACEUTICAL GRADE BP/USP/EP

PACKING: OFFERED IN EXPORT WORTHY PACKING OF 25 KILOS OR AS PER OUR CUSTOMER REQUIREMENTS

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Domperidone Powder

Grade Superior
Shelf Life 1 Year
Mol. Formula C22H24CIN5O2
Mol. Weight 425.91
Melting Range 240-244°C
Supplied By UMA Brothers, India

We are the main supplier of this product.

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Budesonide Liquid

Form Liquid
Cas Number 51333-22-3
Mol. Formula c25h34o6
Mol. Weight 430.53
Melting Range 228°c to 236°c
Storage Cool & Dry Place
Supplied By UMA Brothers, India

Budesonide is a glucocorticoid used in the management of asthma, the treatment of various skin disorders, and allergic rhinitis. Budesonide-d8 is a labeled budesonide, a non-halogenated glucocorticoid related to triamcinolone hexacetonide, which is used as an anti-inflammatory agent.

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Rifampicin

Supplied By UMA Brothers, India

We are offering rifampicin.Rifampicin is a semisynthetic antibiotic produced from streptomyces mediterranei. It has a broad antibacterial spectrum, including activity against several forms of mycobacterium. In susceptible organisms it inhibits dna-dependent rna polymerase activity by forming a stable complex with the enzyme. It thus suppresses the initiation of rna synthesis. Rifampin is bactericidal, and acts on both intracellular & extracellular organismsrifampin is a rifamycin antibacterial. The chemical classification of rifampin is rifamycins. Rifampin is a semisynthetic derivative of rifamycin with broad antibacterial activity. Rifampin inhibits dna-dependent rna polymerase in susceptible bacteria and is often used in combination with other antibiotics for various infections including tuberculosis. synonyms: rifampin; 3-(4-methylpiperazinyl-iminomethyl) rifamycin sv; rifamycin ampcas number: 13292-46-1, mol. Formula: c43h58n4o12, mol.weight: 822.94rifampicin is a red to orange crystalline solid. It is soluble in water (ph 4.3) (1.3 mgml), chloroform, ethyl acetate, methanol (25 mgml), dmso (25 mgml), dimethyl sulfoxide, tetrahydrofuran, and water (ph 7.3) (2.5 mgml) at 25 c with melting point of 183c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Glibenclamide

Supplied By UMA Brothers, India

We are offering glibenclamide.Glyburide is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide. Glyburide is a sulfonylurea. The chemical classification of glyburide is sulfonylurea compounds.Glyburide is a highly protein bound, longer-acting second-generation sulfonylurea with antihyperglycemic activity. Glyburide, also called glibenclamide, is more likely to cause hypoglycemic episodes due to its longer half-life and possible displacement by other highly protein bound drugs. This agent is metabolized into two inactive metabolites which are excreted in the bile and urine. This agent shows peroxisome proliferator-activated receptor gamma (ppargamma) agonistic activity. synonyms: 5-chloro-n-[2-[4-(cyclohexylcarbamoylsulfamoyl) phenyl] ethyl]-2-methoxybenzamidecas number: 10238-21-8, mol. Formula: c23h28cln3o5s, mol.weight: 494glibenclamide is a white crystalline powder. It is soluble in ethanol (5 mgml), dmso (25 mgml), chloroform (1:36), methanol (1:250), and dmf insoluble in water with melting range of 173c to 175c.Standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Xanthinol Nicotinate

Supplied By UMA Brothers, India

We are offering xanthinol nicotinate is a vasodilator used in peripheral vascular disorders and insufficiency. It may cause gastric discomfort and hypotension. Xanthinol niacinate is a combination of xanthinol and niacin which acts as a vasodilator. Studies show that xanthinol niacinate can modulate tumors during their reoxygenation. Xanthinol niacinate also displays anti-platelet and thrombolytic activity. In addition, this compound can reduce whole blood viscosity, as a result of its anti-platelet activity and decrease cholesterol and fibrinogen. synonyms: 7-[2-hydroxy-3-[2-hydroxyethyl (methyl) amino] propyl]-1, 3-dimethylpurine-2, 6-dione; pyridine-3-carboxylic acidcas number: 437-74-1, mol. Formula: c19h26n6o6, mol.weight: 434.45xanthinol nicotinate is a white crystalline solid powder. It is easily soluble in water, little - in alcohol with melting range of 180c to 184c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Ganciclovir

Supplied By UMA Brothers, India

We are offering ganciclovir.Ganciclovir is a cytomegalovirus nucleoside analog dna polymerase inhibitor and nucleoside analog antiviral. The mechanism of action of ganciclovir is as a dna polymerase inhibitor. The chemical classification of ganciclovir is nucleoside analog.an acyclovir analog that is a potent inhibitor of the herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from aids-associated cytomegalovirus infections.Ganciclovir is a synthetic guanine derivative with antiviral activity. As the active metabolite of ganciclovir, ganciclovir-5-triphosphate (ganciclovir-tp) appears to inhibit viral dna synthesis by competitive inhibition of viral dna polymerases and incorporation into viral dna, resulting in eventual termination of viral dna elongation. synonyms: 2-amino-9-(1, 3-dihydroxypropan-2-yloxymethyl)-3h-purin-6-onecas number: 82410-32-0, mol. Formula: c9h13n5o4, mol.weight: 255.23ganciclovir is white powder. It is soluble in 0.1 m hcl (10 mgml), dmso (5 mgml), water (2 mgml), hot methanol, and ethanol (

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Risperidone

Supplied By UMA Brothers, India

We are offering risperidone.Risperidone is a selective blocker of dopamine d2 receptors &serotonin 5-ht2 receptors that acts as an atypical antipsychotic agent. It has been shown to improve both positive and negative symptoms in the treatment of schizophrenia. Risperidone is an atypical antipsychotic.Risperidone is a benzisoxazole derivative with antipsychotic property. risperidone selectively antagonizes serotonin (5-ht) effects via cortical 5-ht2 receptor &to a lesser extent, competes with dopamine at the limbic dopamine d2 receptor. The antagonism leads to decreased psychotic effects, such as hallucinations & delusions. In addition risperidone has low to moderate affinity for histamine h1, 5-ht1a, 5-ht1c, and 5-ht1d receptors, while it has weak affinity for dopamine d1 and haloperidol-sensitive sigma site receptors. synonyms: 3-[2-[4-(6-fluoro-1, 2-benzoxazol-3-yl) piperidin-1-yl] ethyl]-2-methyl-6, 7, 8, 9-tetrahydropyrido [1, 2-a] pyrimidin-4-onecas number: 106266-06-2, mol. Formula: c23h27fn4o2, mol.weight: 410.48risperidone is a crystalline solid. It is soluble in dmso (10 mm), ethanol (10 mm), chloroform, and methanol insoluble in water with melting range of 170c tp 172c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Quinidine

Supplied By UMA Brothers, India

We are offering quinidine is an antiarrhythmic and cytochrome p450 2d6 inhibitor. The mechanism of action of quinidine is as a cytochrome p450 2d6 inhibitor. Quinidine is an alkaloid extracted from the bark of the cinchona tree with class 1a antiarrhythmic and antimalarial effects. Quinidine stabilizes the neuronal membrane by binding to and inhibiting voltage-gated sodium channels, thereby inhibiting the sodium influx required for the initiation and conduction of impulses resulting in an increase of the threshold for excitation and decreased depolarization during phase 0 of the action potential. In addition, the effective refractory period (erp), action potential duration (apd), and erpapd ratios are increased, resulting in decreased conduction velocity of nerve impulses. quinidine exerts its antimalarial activity by acting primarily as an intraeryth rocytic schizonticide through association with the heme polymer (hemazoin) in the acidic food vacuole of the parasite thereby preventing further polymerization by heme polymerase enzyme. This results in accumulation of toxic heme and death of the parasite. synonyms: (s)-[(2r, 4s, 5r)-5-ethenyl-1-azabicyclo [2.2.2] octan-2-yl]-(6-methoxyquinolin-4-yl) methanolcas number: 56-54-2, mol. Formula: c20h24n2o2, mol.weight: 324.42quinidine is white to light yellow crystal powder. It is soluble in methanol, chloroform, alcohol (1 g36ml), water (140 mgl) at 25 c, benzene, dmso(100mm), and slightly soluble in ether, petroleum ether with melting range of 168c to 172c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Nebivolol Hydrochloride

Supplied By UMA Brothers, India

We are offering nebivolol hydrochloride.Nebivolol hydrochloride is a cardioselective adrenergic beta-1 receptor antagonist (beta-blocker) that functions as a vasodilator through the endothelial l-arginine nitric oxide system. It is used to manage hypertension and chronic heart failure in elderly patients.Nebivolol hydrochloride is the hydrochloride salt preparation of nebivolol (sc-279910), a highly selective antagonist of the 1-ar (1-adrenoceptor) (ki = 0.88 nm, 2-adrenoceptor ki = 48 nm). Nebivolol is described to produce vasodilation through inducing vascular production of no, mediated through nebivolol agonism of the 3-adrenoceptor. Nebivolol demonstrates some affinity at the 1-adrenergic (ki = 1160 nm), sr-1a (serotonin 5-ht1a) (ki = 20 nm) and 5-ht2 (ki = 700 nm), dopamine d2 (ki = 4000 nm), and histamine h1 (ki = 2400 nm) receptors. synonyms: (1s)-1-[(2s)-6-fluoro-3, 4-dihydro-2h-chromen-2-yl]-2-[[(2s)-2-[(2r)-6-fluoro-3, 4-dihydro-2h-chromen-2-yl]-2-hydroxyethyl] amino] ethanol; hydrochloridecas number: 152520-56-4, mol. Formula: c22h26clf2no4, mol.weight: 441.9nebivolol hydrochloride is a white to off-white powder. It is soluble in water (

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Tolbutamide Powder

Supplied By UMA Brothers, India

We are offering tolbutamide. Tolbutamide is a sulphonylurea hypoglycemic agent with actions and uses similar to those of chlorpropamide. Tolbutamide is a sulfonylurea. The chemical classification of tolbutamide is sulfonylurea compounds. Tolbutamide is a short-acting, first-generation sulfonylurea with hypoglycemic activity. Compared to second-generation sulfonylureas, tolbutamide is more likely to cause adverse effects, such as jaundice. This agent is rapidly metabolized by cypc29. synonyms: 1-butyl-3-(4-methylphenyl) sulfonylurea cas number: 64-77-7, mol. Formula: c12h18n2o3s, mol.weight: 270.35 tolbutamide is white crystalline powder. It is soluble in dmso or 100% ethanol; insoluble in water with melting range of 128c to 130c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Trimetazidine Dihydrochloride

Supplied By UMA Brothers, India

We are offering trimetazidine dihydrochloride.Trimetazidine dihydrochloride is a vasodilator used in angina of effort or ischemic heart disease. Trazodone is an antidepressant of the serotonin antagonist and reuptake inhibitor (sari) class. It is a phenylpiperazine compound. Trazodone also has antianxiety (anxiolytic) and sleep-inducing (hypnotic) effects. synonyms: 1-[(2, 3, 4-trimethoxyphenyl) methyl] piperazine; dihydrochloridecas number: 13171-25-0, mol. Formula: c14h24cl2n2o3, mol.weight: 339.26trimetazidine dihydrochloride is white crystalline solid powder. It is soluble in methanol with melting range of 228c to 232c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Terbutaline

Supplied By UMA Brothers, India

We are offering terbutaline.Terbutaline is a selective beta-2 adrenergic agonist used as a bronchodilator and tocolytic. Terbutaline is a -adrenoceptor agonist. Terbutaline is an activator of 2-ar. synonyms: 5-[2-(tert-butylamino)-1-hydroxyethyl] benzene-1, 3-diolcas number: 23031-25-6, mol. Formula: c12h19no3, mol.weight: 225.28terbutaline is a white crystalline powder. It is soluble in ethanol and methanol with melting range of 119c to 172c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Lovastatin

Supplied By UMA Brothers, India

We are offering lovastatin.Lovastatin is a fungal metabolite isolated from cultures of aspergillus terreus. The compound is a potent anticholesteremic agent. It inhibits 3-hydroxy-3-methylglutaryl coenzyme a reductase (hydroxymethyl- glutaryl coa reductases) which is the rate-limiting enzyme in cholesterol biosynthesis. It also stimulates the production of low-density lipoprotein receptors in the liver. Lovastatin is a hmg-coa reductase inhibitor. The mechanism of action of lovastatin is as a hydroxymethylglutaryl-coa reductase inhibitor.Lovastatin is a lactone metabolite isolated from the fungus aspergillus terreus with cholesterol-lowering and potential antineoplastic activities lovastatin is hydrolyzed to the active beta-hydroxyacid form, which competitively inhibits 3-hydroxyl-3-methylgutarylcoenzyme a (hmg-coa) reductase, an enzyme involved in cholesterol biosynthesis. In addition, this agent may induce tumor cell apoptosis and inhibit tumor cell invasiveness, possibly by inhibiting protein farnesylation and protein geranylgeranylation, and may arrest cells in the g1 phase of the cell cycle. The latter effect sensitizes tumor cells to the cytotoxic effects of ionizing radiation. synonyms: [(1s, 3r, 7s, 8s, 8ar)-8-[2-[(2r, 4r)-4-hydroxy-6-oxooxan-2-yl]ethyl]-3, 7-dimethyl-1, 2, 3, 7, 8, 8a-hexahydronaphthalen-1-yl] (2s)-2-methylbutanoatecas number: 75330-75-5, mol. Formula: c24h36o5, mol.weight: 404.54lovastatin is a white solid. It is soluble in dmso (10 mgml), ethanol (10 mgml), methanol, chloroform, acetone, acetonitrile, dmf, and water (0.4 gml) with melting point of 175c.Standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Calcium Dobesilate

Supplied By UMA Brothers, India

Calcium dobesilate is a drug used to reduce hemorrhage in diabetic retinopathy. Calcium dobesilate is a vasoactive drug with presumed effects on endothelial integrity, capillary permeability and blood viscosity. It is often recommended for venous disorders, and also prescribed for diabetic retinopathy and other microvascular disorders.Calcium dobesilate has a comprehensive mode of action. It increases endothelial nitric oxide levels by enhancing the activity of nitric oxide synthase and decreasing capillary hyperpermeability.calcium dobesilate shows anti-platelet and fibrinolytic activities by inhibiting platelet activation factor (paf) and enhancing the release of tissue plasminogen activator (tpa), thereby improving the local blood flow to tissues, otherwise inhibited due to thrombosis. Calcium dobesilate also inhibits the two pathophysiological reactions in diabetes, viz. Polyol pathway and glycation of proteins, due to its inhibitory effects on aldose reductase.Synonyms: calcium; 2, 5-dihydroxybenzenesulfonatecas number: 20123-80-2, mol. Formula: 2c6h5o5s.ca, mol.weight: 418.41calcium dobesilate is a white powder. It is soluble in water with melting point of 251c.Standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Paclitaxel

Supplied By UMA Brothers, India

We are offering paclitaxel is a cyclodecane isolated from the bark of the pacific yew tree, taxus brevifolia. It stabilizes microtubules in their polymerized form leading to cell death. Paclitaxel is a microtubule inhibitor. The physiologic effect of paclitaxel is by means of microtubule inhibition.Paclitaxel is a compound extracted from the pacific yew tree taxus brevifolia with antineoplastic activity. Paclitaxel binds to tubulin and inhibits the disassembly of microtubules, thereby resulting in the inhibition of cell division. This agent also induces apoptosis by binding to and blocking the function of the apoptosis inhibitor protein bcl-2 (b-cell leukemia 2). synonyms: n-benzyl-beta-phenylisoserine ester;paclitaxel, taxus brevifolia;paclitaxel, taxus species; paclitaxol; paclitaxel; taxol(tm); taxol a;taxol equivalentcas number: 33069-62-4, mol. Formula: c47h51no14, mol.weight: 853.91paclitaxel is off-white powder. It is soluble in ethanol (1.5 mgml), dmso (5 mgml), acetonitrile, methanol (50 mgml), chloroform, 1:10 dmso: pbs(ph 7.2) (0.1 mgml), and dmf (5 mgml) insoluble in water with melting range of 213c to 216c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Potassium Glycerophosphate

Supplied By UMA Brothers, India

We are offering potassium glycerophosphate. avail from us accurately formulated potassium glycerophosphate. The chemical is composed under strict supervision of experts. Potassium glycerophosphate is one of the most absorbable forms of potassium available. In the glycerophosphate form, the potassium is highly soluble in water. We offer potassium glycerophosphate at market leading prices. details :

appearance : pale yellow liquid of 50 - 75% concentration
chemical formula : c3h7k206p 3h20
molecular weight : 302.30
content : pot.glycrophosphate (3 hydrated) should not contain less than 80.0 % of pot.glycerophosphate (c3h7k2o6p) & pot.glycero phosphate solution (50 -75% concentration) contains 95.0 - 105.0% of the specified content of potassium glycerophosphate

benefits :

facilitates functioning of nerve firing and muscular contraction
helps reduce muscle soreness
regulates water balance
needed for the synthesis of dietary proteins

Additional Information:

Payment Terms : L/C, T/T

Packaging Details : OFFERED IN EXPORT WORTHY PACKING OF 25 KILOS OR AS PER OUR CUSTOMER REQUIREMENTS

Delivery Time : 4-5 weeks

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Ashok Shah (Uma Brothers)
C-110, Bhaveshwar Plaza, 189, Lbs Marg, Ghatkopar West., Mumbai, Maharashtra - 400086, India
http://www.umabrothers.in
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