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A potent and specific inhibitor of peptidyl-dipeptidase a. It blocks the conversion of angiotensin I to angiotensin ii, a vasoconstrictor and important regulator of arterial blood pressure. Captopril acts to suppress the renin-angiotensin system and inhibits pressure responses to exogenous angiotensin. Captopril is an angiotensin converting enzyme inhibitor. The mechanism of action of captopril is as an angiotensin-converting enzyme inhibitor. Captopril is a sulfhydryl-containing analog of proline with antihypertensive activity and potential antineoplastic activity. Captopril competitively inhibits angiotensin converting enzyme (ace), thereby decreasing levels of angiotensin ii, increasing plasma renin activity, and decreasing aldosterone secretion. This agent may also inhibit tumor angiogenesis by inhibiting endothelial cell matrix metalloproteinases (mmps) and endothelial cell migration. Captopril may also exhibit antineoplastic activity independent of effects on tumor angiogenesis. synonyms: (2s)-1-[(2s)-2-methyl-3-sulfanylpropanoyl] pyrrolidine-2-carboxylic acid cas number: 62571-86-2, mol. Formula: c9h15no3s, mol.weight: 217.29 captopril is a white to off-white, crystalline powder. It is soluble in water (160 mgml) at 25 c, sesame and corn oils (100 mgml), ethanol (>100 mgml), isopropanol (>100 mgml), chloroform (>100 mgml), and dichloromethane (>100 mgml) with melting range of 104cto 108c. Standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements
Sumatriptan Is A Serotonin Agonist That Acts Selectively At 5ht1 Receptors. It Is Used In The Treatment Of Migraine Disorders. Sumatriptan Is A Serotonin-1b And Serotonin-1d Receptor Agonist. The Mechanism Of Action Of Sumatriptan Is As A Serotonin 1b Receptor Agonist & Serotonin 1d Receptor Agonist.
Sumatriptan Is A Sulfonamide Triptan With Vasoconstrictor Activity. Sumatriptan Selectively Binds To & Activates Serotonin 5-Ht1d Receptors In The Central Nervous System (CNS), Thereby Constricting Cerebral Blood Vessels. This May Lead To A Relief In Pain From Vascular Headaches. Sumatriptan May Also Relieve Vascular Headaches By Decreasing The Release Of Vasoactive Neuropeptides From Perivascular Trigeminal Axons In The Dura Mater During A Migraine, By Reducing Extravasation Of Plasma Proteins, And By Decreasing The Release Of Other Mediators Of Inflammation From The Trigeminal Nerve.
Sumatriptan Is A White Crystalline Solid Or Powder. It Is Soluble In water, 2.14x10+4 Mg/L At 25 Deg C (EST) With Melting Range Of 169°C TO 171°C.
