Lomustine

We are offering lomustine.
Lomustine is an alkylating agent of value against both hematologic malignancies and solid tumors. Lomustine is an alkylating drug. The mechanism of action of lomustine is as an alkylating activity.
Lomustine is a nitrosourea with antineoplastic activity. lomustine alkylates and crosslinks dna, thereby inhibiting dna and rna synthesis. This agent also carbamoylates dna and proteins resulting in inhibition of dna & rna synthesis and disruption of rna processing. Lomustine is lipophilic and crosses the blood-brain barrier.
synonyms: 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea
cas number: 13010-47-4, mol. Formula: c9h16cln3o2, mol.weight: 233.7
lomustine is a white to yellow powder. It is soluble in ethanol (47 mgml at 25 °c), chloroform, water (