CETIRIZINE DI HYDROCHLORIDE

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SYNONYMS: 2-[2-[4-[(4-CHLOROPHENYL)-PHENYLMETHYL] PIPERAZIN-1-YL] ETHOXY] ACETIC ACID, DIHYDROCHLORIDE CAS NUMBER: 83881-51-1, MOL.FORMULA:C21H23CLN2O3·2HCL, MOL. WEIGHT: 461.82

IT IS WHITE COLOUR POWDER WITH AND MELTING RANGE OF 210°C TO 218°C. IT IS SOLUBLE IN WATER.

STANDARD: OFFERED OF PHARMACEUTICAL GRADE BP/USP/EP – LEVO CETIRIZINE ALSO OFFERED

PACKING: OFFERED IN EXPORT WORTHY PACKING OF 25 KILOS OR AS PER OUR CUSTOMER REQUIREMENTS

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We are offering verapamil hydrochloride.Verapamil hydrochloride is a -adrenergic receptor (-ar) antagonist and calcium channel protein inhibitor that blocks the l-type ca2+ channels in smooth and cardiac muscle cells. Verapamil is an anti- arrhythmic agent and vasodilator known to reduce the renal clearance of digoxin and induce apoptosis in primary and metastatic colon adeno- carcinoma human cell lines in vitro. It has been observed that verapamil can induce currents by itself, presumably by acting on the potassium and chloride leakage. Verapamil has also been used as an inhibitor of drug efflux pump proteins such as mdr (p-glycoprotein). Verapamil is a substrate of cyp3a4 and cyp2c6. synonyms: 2-(3, 4-dimethoxyphenyl)-5-[2-(3, 4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile;hydrochloridecas number: 152-11-4, mol. Formula: c27h39cln2o4, mol.weight: 491.06verapamil hydrochloride is a white to off-white powder. It is soluble in water (83 mgml), ethanol (200 proof) (26 mgml), methanol (>100 mgml), propylene glycol (93 mgml), ethanol (190 proof) (>100 mgml), 2-propanol (4.6 mgml), ethyl acetate (1.0 mgml), dmf (>100 mgml), dichloromethane (>100 mgml), chloroform (sparingly) at 21 c, and hexane (0.001 mgml) with melting point of 142c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Pioglitazone Hydrochloride

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We are offering pioglitazone hydrochloride is the hydrochloride salt preparation of pioglitazone, a specific ligand of ppar- (peroxisome proliferator-activated receptor-). Pioglitazone is a thiazolidinedione compound described to produce antiinflammatory and antiarteriosclerotic effects. Pioglitazone is demonstrated to prevent l-name-induced coronary inflammation and arteriosclerosis and to suppress increased tnf- mrna produced by aspirin-induced gastric mucosal injury. Pioglitazone hydrochloride is an activator of ppar . synonyms: 5-[[4-[2-(5-ethylpyridin-2-yl) ethoxy] phenyl] methyl]-1, 3-thiazolidine-2, 4-dione; hydrochloridecas number: 112529-15-4, mol. Formula: c19h21cln2o3s, mol.weight: 392.9pioglitazone hydrochloride is a white crystalline powder. It is soluble in water (

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Dorzolamide Hydrochloride

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We are offering dorzolamide hydrochloride is the hydrochloride salt form of dorzolamide, an inhibitor of carbonic anhydrase, a zinc-containing enzyme that catalyzes the rapid conversion of carbon dioxide and water into carbonic acid, protons and bicarbonate ions. Distributed throughout many cells and tissues, various carbonic anhydrases play important roles in mineral and metabolic homeostasis. synonyms: (4s, 6s)-4-(ethylamino)-6-methyl-7, 7-dioxo-5, 6-dihydro-4h-thieno [2, 3-b] thiopyran-2-sulfonamide; hydrochloridecas number: 130693-82-2, mol. Formula: c10h17cln2o4s3, mol.weight: 360.9dorzolamide hydrochloride is white powder. It is soluble in water (14 mgml at 25 c), methanol, dmso (

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Terbinafine Hydrochloride

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We are offering terbinafine hydrochloride is a synthetic allylamine derivative structurally related to naftifine, antifungal terbinafine hydrochloride blocks ergosterol biosynthesis by inhibition ofsqualene epoxidase, part of the sterol synthesis pathway for the fungal cell membrane. Highly lipophilic, it tends to accumulate in skin, nails, and fatty tissues. Terbinafine is active against dermatophytes. synonyms: (e)-n, 6, 6-trimethyl-n-(naphthalen-1-ylmethyl) hept-2-en-4-yn-1-amine; hydrochloridecas number: 78628-80-5, mol. Formula: c21h26cln, mol.weight: 327.89terbinafine hydrochloride is a white crystalline powder. It is soluble in methanol, ethanol (30 mgml), methylene chloride, dmso (10 mgml), dmf (10 mgml), and 1:2 solution of ethanol: pbs (ph 7.2) (0.3 mgml) insoluble in water with melting point of 214c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Venlafaxine Hydrochloride

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We are offering venlafaxine hydrochloride is a cyclohexanol and phenylethylamine derivative that functions as a serotonin and noradrenaline reuptake inhibitor (snri) and is used as an antidepressive agent. Venlafaxine hydrochloride is a dual st and slc6a2 (serotonin and noradrenalin re-uptake) inhibitor that displays 30-fold higher affinity for st (sert) (ki = 82 nm) than slc6a2 (net) (ki = 2480 nm). synonyms: 1-[2-(dimethylamino)-1-(4-methoxyphenyl) ethyl] cyclohexan-1-ol; hydrochloridecas number: 99300-78-4, mol. Formula: c17h28clno2, mol.weight: 313.86venlafaxine hydrochloride is white crystalline powder. It is soluble in water (>25 mgml), and dmso (50 mm) with melting range of 207c to 209c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Benazepril Hydrochloride

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We are offering benazepril hydrochloride.Benazepril hydrochloride is the hydrochloride salt of benazepril, a carboxyl-containing angiotensin-converting enzyme (ace) inhibitor with antihypertensive activity. As a prodrug, benazepril is metabolized to its active form benazeprilat. Benazeprilat competitively binds to and inhibits ace, thereby blocking the conversion of angiotensin I to angiotensin ii. This prevents the potent vasoconstrictive actions of angiotensin ii, resulting in vasodilation. Benazeprilat also decreases angiotensin ii-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow. Benazepril is a prodrug which is metabolized by the liver into its active formbenazeprilat via cleavage of the drug's ester group. synonyms: 2-[(3s)-3-[[(2s)-1-ethoxy-1-oxo-4-phenylbutan-2-yl] amino]-2-oxo-4, 5-dihydro-3h-1-benzazepin-1-yl] acetic acid; hydrochloridecas number: 86541-74-4, mol. Formula: c24h29cln2o5, mol.weight: 460.95benazepril hydrochloride is a white crystalline solid powder. It is soluble in water (50 mm), dmso (100 mm), ethanol, and methanol with melting range of 188c to 190c.Standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Doxepin Hydrochloride

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We are offering doxepin hydrochloride.Doxepin hydrochloride is a dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine h (1) - and h (2)-receptors.Doxepin hydrochloride is a dibenzoxepin derivative and tricyclic anti- depressant with antipruritic and sedative activities. Doxepin blocks the reuptake of norepinephrine and serotonininto presynaptic terminals thereby prolonging the availability of the monoaminergic neurotran smitters within the synaptic cleft and enhancing their action leading to sedative effects.doxepin also has antagonistic effects on histamine (h1 and h2), 5-ht2, alpha-1 adrenergic, and muscarinic receptors. The antipru- ritic effect of this agent is the result mediated through inhibition of histamine receptors. synonyms: (3e)-3-(6h-benzo[c] [1] benzoxepin-11-ylidene)-n, n-dimethylpropan-1-amine; hydrochloridecas number: 1229-29-4, mol. Formula: c19h22clno, mol.weight: 315.84doxepin hydrochloride is a white solid powder. It is soluble in water (100 mm), chloroform (1:2), alcohol (1:1), methanol, and dmso with melting range of 188c to 189c.Standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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2+

Moxifloxacin Hydrochloride

Purity 99%
Cas Number 186826-86-8
Mol. Formula C21H25CLFN3O4
Mol.weight 437.89
Standard Offered of Pharmaceutical Grade BP/USP/EP
Packing Offered in Export Worthy Packing of 25 Kilos or as per Our Customer Requirements
Supplied By UMA Brothers, India

Moxifloxacin Hydrochloride Is The Hydrochloride Salt Preparation Of Moxifloxacin, An 8-Methoxy-Fluoroquinone Compound With Broad-Spectrum Bactericidal Activity Against Gram-Positive & Gram-Negative Strains. 8-Methoxy-Fluoroquinones Are Described To Inhibit The Activities Of Topo Ii (DNA Gyrase) & Topoisomerase Iv. The 8-Methoxy Group Of Moxifloxacin Is Suggested To Confer A Lowered Propensity For Resistance Development As Compared To Other C-8 Substituted Quinolones, & Moxifloxacin Demonstrates Potent Activity Against Wild-Type And First-Step Gyrase- & Topoisomerase Iv-Resistant Mutants. Moxifloxacin Shows Activity Against Methicillin-Susceptible Staphy Lococci, Penicillin-Susceptible And Penicillin-Resistant Pneumococci, Penicillin-Susceptible & Penicillin-Resistant Viridans Group streptococci, Group A streptococci, m. Catarrhalis, & H. Influenzae in Vitro.

Synonyms : 7-[(4as, 7as)-1, 2, 3, 4, 4a, 5, 7, 7a-Octahydropyrrolo[3, 4-B]Pyridin-6-Yl]-1-Cyclopropyl-6-Fluoro-8-Methoxy-4-Oxoquinoline-3-Carboxylic Acid;Hydrochloride.
Moxifloxacin Hydrochloride is a Slightly Yellow to Yellow Crystalline Substance. It is Sparingly Soluble in Water (24 Mg/ml), Dmso (88 Mg/ml At 25 °c), and Ethanol (<1 Mg/ml At 25 °c) with Melting Ran.

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Labetalol Hydrochloride

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We are offering labetalol hydrochloride.Labetalol hydrochloride is a salicylamide derivative that is a non-cardioselective blocker of beta-adrenergic receptors and alpha-1 adrenergic receptors.Labetalol hydrochloride is the hydrochloride form of labetalol, a third generation selective alpha-1-adrenergic antagonist and non-selective beta-adrenergic antagonist with vasodilatory and antihyper- tensive properties. Labetalol competitively binds to alpha-1-adrenergic receptors in vascular smooth muscle, thereby inhibiting the adrenergic stimulation of endothelial cell function and vasoconstriction in peripheral blood vessels. This agent also binds to beta-receptors in the bronchial and vascular smooth muscle, resulting in a decrease in adrenergic stimulation. The result is a decrease in resting & exercises heart rates, cardiac output, and in both systolic and diastolic blood pressure, thereby resulting in vasodilation, and negative chronotropic and inotropic cardiac effects. synonyms: 2-hydroxy-5-[1-hydroxy-2-(4-phenylbutan-2-ylamino) ethyl] benzamide; hydrochloridecas number: 32780-64-6, mol. Formula: c19h25cln2o3, mol.weight: 364.87labetalol hydrochloride is white solid powder. It is soluble in h2o: soluble: ethanol: soluble with melting range of 178c to 180c.Standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Ambroxol Hydrochloride

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Ambroxol hydrochloride is a metabolite of bromhexine that stimulates mucociliary action and clears the air passages in the respiratory tract. It is usually administered as the hydrochloride. It is the active ingredient of mucosolvan, mucobrox, mucol, lasolvan, mucoangin, surbronc, ambolar, and lysopain. The substance is a mucoactive drug with several properties including secretolytic and secretomotoric actions that restore the physiological clearance mechanisms of the respiratory tract, which play an important role in the bodys natural defence mechanisms.Ambroxol is indicated as secretolytic therapy in bronchopulmonary diseases associated with abnormal mucus secretion and impaired mucus transport. It promotes mucus clearance, facilitates expectoration and eases productive cough, allowing patients to breath.

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Reserpine Hydrochloride

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We are offering reserpine hydrochloride is an indole alkaloid antipsychotic, & antihypertensive drug that has been used for the control of high blood pressure & for the relief of psychotic symptoms although because of the development of better drugs for these purposes & because of its numerous side- effects, it is rarely used today. The antihypertensive actions of reserpine are a result of its ability to deplete catechola- mines (among other monoamine neurotransmitters) from peripheral sympathetic nerve endings. These substances are normally involved in controlling heart rate, force of cardiac contraction and peripheral vascular resistance. Moreover, reserpine has a peripheral action in many parts of the body, resulting in a preponderance of the effects of thecholinergic part of the autonomous nervous system on the gi tract, smooth muscles, blood vessels, etc. synonyms: methyl (1r, 15s, 17r, 18r, 19s, 20s)-6, 18-dimethoxy-17-(3, 4, 5-trimethoxybenzoyl)oxy-1, 3, 11, 12, 14, 15, 16, 17, 18, 19, 20, 21-dodecahydroyohimban-19-carboxylate;hydrochloridecas number: 16994-56-2, mol. Formula: c33h40n2o9.clh, mol.weight: 645.13reserpine hydrochloride is a white or pale buff to slightly yellow coloured. It is freely soluble in chloroform, methylene, chloride, glacial acid; soluble in dmso (4 mgml), benzene, ethyl acetate; slightly soluble in methanol (0.28 mgml), with melting point of 265c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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BETAXOLOL HYDROCHLORIDE

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We are offering betaxolol hydrochloride is a cardioselective beta-1-adrenergic antagonist with no partial agonist activity. Betaxolol hydrochloride is the hydrochloride salt form of betaxolol, a beta-1-selective adrenergic receptor antagonist without intrinsic sympathomimetic activity. Betaxolol hydrochloride acts on the heart and circulatory system and decreases cardiac contractility and rate, thereby reducing cardiac output. When applied topically in the eye, it lowers intraocular pressure by reducing aqueous humor secretion.Betaxolol hydrochloride is a selective 1-ar adrenoceptor antagonist. Adrenoreceptors or adrenergic receptors are g protein-coupled proteins involved in a variety of sympathetic nervous system activities. 1-ar is primarily associated with cardiac output effects. synonyms: 1-[4-[2-(cyclopropylmethoxy) ethyl] phenoxy]-3-(propan-2-ylamino) propan-2-ol; hydrochloridecas number: 63659-19-8, mol. Formula: c18h30clno3, mol.weight: 343.89betaxolol hydrochloride is a white solid powder. It is soluble in water (50 mm) with melting point of 62c.Standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Ranitidine Hydrochloride

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We are offering ranitidine hydrochloride.Ranitidine hydrochloride is a non-imidazole blocker of those histamine receptors that mediate gastric secretion (h2 receptors). It is used to treat gastrointestinal ulcers.Ranitidine is a medication that decreases stomach acid production. It is commonly used in treatment of peptic ulcer disease, gastroesophageal reflux disease, and zollingerellison syndrome. There is also tentative evidence of benefit for hives. It can be taken by mouth, by injection into a muscle, or into a vein. synonyms: (e)-1-n'-[2-[[5-[(dimethylamino) methyl] furan-2-yl] methyl sulfanyl] ethyl]-1-n-methyl-2-nitroethene-1, 1-diamine; hydrochloridecas number: 66357-35-5, mol. Formula: c13h22n4o3s, mol.weight: 314.4ranitidine hydrochloride is a white solid powder. It is soluble in water with melting range of 69c to 72c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Triprolidine Hydrochloride

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We are offering triprolidine hydrochloride.Triprolidine hydrochloride is a component of cough and cold medicines. It may cause drowsiness. Histamine h1 antagonist used in allergic rhinitis; asthma; and urticaria. synonyms: 2-[(e)-1-(4-methylphenyl)-3-pyrrolidin-1-ylprop-1-enyl] pyridine; hydrochloridecas number: 6138-79-0, mol. Formula: c19h23cln2, mol.weight: 314.85triprolidine hydrochloride is white crystalline solid powder. It is soluble in water (100 mgml), alcohol (1:1.5), and chloroform (1:

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Sotalol Hydrochloride

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We are offering sotalol hydrochloride.Sotalol hydrochloride is a compound categorized with class iii antiarrhythmic activity with a mechanism of action that prolongs the action potential and refraction of cardiac tissue through non-selective yet potent -adronergic blocking activity. Sotalol hydrochloride is also considered a non-selective blocker and a potassium channel blocker with an ic50 of 43 m. synonyms: n-[4-[1-hydroxy-2-(propan-2-ylamino) ethyl] phenyl] methanesulfonamide; hydrochloridecas number: 959-24-0, mol. Formula: c12h21cln2o3s, mol.weight: 308.82sotalol hydrochloride is a white crystalline solid. It is soluble in phosphate buffered saline (100 mm), dmso (62 mgml at 25 c), ethanol (

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Epirubicin Hydrochloride

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We are offering epirubicin hydrochloride.Epirubicin hydrochloride is an anthracycline which is the 4'-epi-isomer of doxorubicin. The compound exerts its antitumor effects by interference with the synthesis and function of dna.Epirubicin hydrochloride is the hydrochloride salt of the 4'-epi-isomer of the anthracycline antineoplastic antibiotic doxorubicin. epirubicin intercalates into dna and inhibits topoisomerase ii, thereby inhibiting dna replication and ultimately, interfering with rna and protein synthesis. This agent also produces toxic free-radical intermediates and interacts with cell membrane lipids causing lipid peroxidation. synonyms: (7s, 9s)-7-[(2r, 4s, 5r, 6s)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6, 9, 11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8, 10-dihydro-7h-tetracene-5, 12-dione;hydrochloridecas number: 56390-09-1, mol. Formula: c27h30clno11, mol.weight: 579.98epirubicin hydrochloride is orange-red crystalline solid. It is soluble in water (116 mgml) at 25 c, dmso (116 mgml) at 25 c, ethanol (3 mgml) at 25 c, acetone, and methanol with melting point of 185c.Standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Dobutamine Hydrochloride

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We are offering dobutamine hydrochloride is a catecholamine derivative with specificity for beta-1 adrenergic receptors. It is commonly used as a cardiotonic agent after cardiac surgery and during dobutamine stress echocardiography.Dobutamine hcl is the hydrochloride salt form of dobutamine, a synthetic catecholamine with direct inotropic activity. Dobutamine hydrochloride mimics the effects ofdopamine and stimulates beta-1 adrenergic receptors located in the myocardium. This leads to an increase in heart rate and force and results in an increase in cardiac output. synonyms: 4-[2-[4-(4-hydroxyphenyl) butan-2-ylamino] ethyl] benzene-1, 2-diol; hydrochloridecas number: 49745-95-1, mol. Formula: c18h24clno3, mol.weight: 337.84dobutamine hydrochloride is a white to off-white solid. It is soluble in water (10 mgml, with gentle heating), ethanol (20 mgml, with gentle heating), methanol, pyridine, and dmso (100 mm) with melting range of 188c to 189c.Standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Imipramine Hydrochloride

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We are offering imipramine hydrochloride.Imipramine hydrochloride is the prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.Imipramine hydrochloride is the hydrochloride salt form of imipramine, a synthetic tricyclic derivative antidepressant imipramine enhances monoamine neurotransmission in certain areas of the brain. It also induces sedation through histamine 1 receptor blockage; hypotension through beta-adrenergic blockage; and diverse parasympatholytic effects.imipramine has less sedative effect than other members of its therapeutic family. It is used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. synonyms: 3-(5, 6-dihydrobenzo [b] [1] benzazepin-11-yl)-n, n-dimethylpropan-1-amine; hydrochloridecas number: 113-52-0, mol. Formula: c19h25cln2, mol.weight: 316.87imipramine hydrochloride is a white solid powder. It is soluble in chloroform and dichloromethane with melting range of 173c to 175c.Standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Naphazoline Hydrochloride

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We are offering naphazoline hydrochloride.Naphazoline hydrochloride is an adrenergic vasoconstrictor agent used as a decongestant.Naphazoline hydrochloride is the hydrochloride salt form of naphazoline, an imidazole derivative and a direct-acting sympathomimetic amine with vasoconstrictive properties. Upon ocular administration, naphazoline hydrochloride exerts its effect by acting on alpha- adrenergic receptors in the arterioles of the conjunctiva to produce vasoconstriction, resulting in decreased conjunctival congestion and diminished itching, irritation and redness. synonyms: 2-(naphthalen-1-ylmethyl)-4, 5-dihydro-1h-imidazole; hydrochloridecas number: 550-99-2, mol. Formula: c14h15cln2, mol.weight: 246.74naphazoline hydrochloride is a white crystalline powder. It is soluble in water (170 mgml at 20 c), alcohol (freely), dmso (17 mgml at 25 c), ethanol (22 mgml at 25 c), and chloroform (slightly) with melting range of 258c to 260c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Raloxifene Hydrochloride

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We are offering raloxifene hydrochloride.Raloxifene hydrochloride is a second generation selective estrogen receptor modulator (serm) used to prevent osteoporosis in postmeno- pausal women. It has estrogen agonist effects on bone and cholesterol metabolism but behaves as a complete estrogen antagonist on mammary gland and uterine tissue.Raloxifene hydrochloride is the hydrochloride salt form of raloxifene, a selective benzothiophene estrogen receptor modulator (serm) with lipid lowering effects and activity against osteoporosis. Raloxifene hydrochloride specifically binds to estrogen receptors in responsive tissue, including liver, bone, breast and endometrium. A resulting ligand-receptor complex is translocated to the nucleus where, depending on the tissue type it promotes or suppresses the transcription of estrogen-regulated genes thereby exerting its agonistic or antagonistic effects. This agent functions as an estrogen agonist in lipid metabolism, thereby decreasing total and ldl cholesterol levels. In tissue like bone, it decreases bone resorption and bone turnover and increases bone mineral density. Raloxifene hydrochloride acts as an estrogen antagonist in uterine and breast tissue. This agent also exerts an anti-proliferative effect on estrogen-sensitive breast cancer. synonyms: [6-hydroxy-2-(4-hydroxyphenyl)-1-benzothiophen-3-yl]-[4-(2-piperidin-1-ylethoxy) phenyl] methanone; hydrochloridecas number: 82640-04-8, mol. Formula: c28h28clno4s, mol.weight: 510.04raloxifene hydrochloride is a light-yellow solid powder. It is soluble in dmso (50 mm), methanol, and ethanol (

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Ritodrine Hydrochloride

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We are offering ritodrine hydrochloride is a 2-ar (2-adrenoceptor) agonist that acts as an adrenergic receptor stimulant. Gives priority to act on the adrenergic receptors on the uterine smooth muscle through membrane-mediated effects of uterine smooth muscle cells, and uterine smooth muscle cells 2-ar (2-adrenoceptor) which activates cell membrane adenylate cyclase to adenosine triphosphate into cyclic adenosine monophosphate (camp), leading to increased intracellular camp, thus reducing myosin light chain kinase activity in reducing intracellular calcium concentration at the same time. synonyms: 4-[2-[[(1s, 2r)-1-hydroxy-1-(4-hydroxyphenyl) propan-2-yl] amino] ethyl] phenol; hydrochloridecas number: 23239-51-2, mol. Formula: c17h22clno3, mol.weight: 323.81ritodrine hydrochloride is a off-white solid. It is soluble in water (50 mgml), dmso, and methanol with melting range of 195c tp 197c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Tizanidine Hydrochloride

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We are offering tizanidine hydrochloride.Tizanidine hydrochloride is the hydrochloride salt form of tizanidine, an imidazoline derivative structurally similar to clonidine and an adrenergic agonist with muscle relaxant property. Tizanidine stimulates alpha-2 adrenergic receptors in the central nervous system, thereby inhibiting presynaptic release of norepinephrine & increasing the inhibitory effect on alpha motor neurons & motor reflexes. tizanidine exerts some activity at the postsynaptic excitatory amino acid receptors & imidazoline receptors which may contribute to the overall reduction in facilitation of spinal motor neurons. Overall tizanidine hydrochloride causes muscle relaxation reduces spasticity & antinociceptive effects. synonyms: 5-chloro-n-(4, 5-dihydro-1h-imidazol-2-yl)-2, 1, 3-benzothiadiazol-4-amine; hydrochloridecas number: 64461-82-1, mol. Formula: c9h9cl2n5s, mol.weight: 290.17tizanidine is a off-white to pale yellow solid. It is soluble in water (20 mgml), methanol, and dmso (100 mm) with melting point of 280c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Topotecan Hydrochloride

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We are offering topotecan hydrochloride.Topotecan hydrochloride is an antineoplastic agent used to treat ovarian cancer. It works by inhibiting dna topoisomerases, type i. Topotecan hydrochloride is the hydrochloride salt of a semisynthetic derivative of camptothecin with antineoplastic activity. During the s phase of the cell cycle, topotecan selectively stabilizes topoisomerase i-dna covalent complexes, inhibiting religation of topoisomerase i-mediated single-strand dna breaks and producing potentially lethal double-strand dna breaks when complexes are encountered by the dna replication machinery. Camptothecin is a cytotoxic quinoline-based alkaloid extracted from the asian tree camptotheca acuminata. synonyms: topotecan monohydrochloride; topotecan hcl; skf-104864a; 9-[(dimethylamino) methyl]-10-hydroxy-(20s)-camptothecin, hclcas number: 119413-54-6, mol. Formula: c23h24cln3o5, mol.weight: 457.91topotecan hydrochloride is white crystalline solid powder. It is soluble in methanol, water (92 mgml at 25 c), dmso (92 mgml at 25 c), ethanol (

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Trihexyphenidyl Hydrochloride

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We are offering trihexyphenidyl hydrochloride.D, l-trihexyphenidyl, hydrochloride is an anticholinergic tertiary amine that can gain access to the cns. It is used to treat parkinsonism and the extrapyramidal side effects of anti-psychotic drugs. synonyms: 1-cyclohexyl-1-phenyl-3-piperidin-1-ylpropan-1-ol; hydrochloridecas number: 58947-95-8, mol. Formula: c20h31no hcl, mol.weight: 337.92trihexyphenidyl hydrochloride is white solid powder. It is soluble in methanol 50 mgml and slightly soluble in water with melting range of 247c to 249c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Ziprasidone Hydrochloride

Supplied By UMA Brothers, India

We are offering ziprasidone hydrochloride monohydrate is an atypical antipsychotic that displays combined sr-2a and d2dr inhibition. Ziprasidone displays high affinity at sr-2a receptors with a sr-2ad2dr affinity ratio greater than any other clinically available atypical antipsychotics (pki values are 9.38, 8.88, 8.69, 8.47, 8.32, 8.14, 7.98, 7.49, 7.33 and 6.28 for sr-2a, 5-ht2c, 5-ht1d, 5-ht1a, d2dr, d3, 1, d4, h1 and d1 receptors respectively). synonyms: 5-[2-[4-(1, 2-benzothiazol-3-yl) piperazin-1-yl] ethyl]-6-chloro-1, 3-dihydroindol-2-one; hydrochloridecas number: 138982-67-9, mol. Formula: c21h21cln4os.clh.h2o, mol.weight: 467.42ziprasidone hydrochloride is a pale tan powder. It is soluble in dmso (>10 mgml), dmf (0.16 mgml), and 1: 2 solution of dmso: pbs (ph 7.2) (0.33 mgml) insoluble in water with melting point of 300c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Bromhexine Hydrochloride

Supplied By UMA Brothers, India

We are offering bromhexine hydrochloride.Bromhexine hydrochloride is a mucolytic agent that exerts both a secretagogic action on submucosal glands and a mucolytic action toward acid glycoproteins inside cells. Bromhexine is intended to support the body's mechanisms for clearing mucus from the respiratory tract. This contributes to a secretomotoric effect by helping the cilia transport the phlegm out of the lungs. For this reason it is often added to cough syrups. Bromhexine is a synthetic derivative of the herbal active ingredient vasicine. It has been shown to increase the proportion of serous bronchial secretion, making it more easily expectorated. It is indicated as "secretolytic therapy in bronchopulmonary diseases associated with abnormal mucus secretion and impaired mucus transport" synonyms: 2, 4-dibromo-6-[[cyclohexyl (methyl) amino] methyl] aniline; hydrochloridecas number: 611-75-6, mol. Formula: c14h20br2n2 hcl, mol.weight: 412.60bromhexine is a white solid powder. It is soluble in water (

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Cyproheptadine Hydrochloride

Supplied By UMA Brothers, India

We are offering cyproheptadine hydrochloride.Cyproheptadine hydrochloride is a serotonin antagonist and a histamine h1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.Cyproheptadine hydrochloride is the hydrochloride salt of a synthetic methyl-piperidine derivative with antihistaminic and anti-serotoninergic properties. Cyproheptadine competes with free histamine (ha) for binding at ha-receptor sites, thereby competitively antagonizing histamine stimulation of ha-receptors in the gastrointestinal tract, large blood vessels, and bronchial smooth muscle. This agent also competes with free serotonin for binding at serotonin receptor sites. Cypro hepta dine exhibits anticholinergic and sedative properties and has been shown to stimulate appetite and weight gain. synonyms: 4-(dibenzo [1, 2-a: 1', 2'-e] [7] annulen-11-ylidene)-1-methyl piperidine; hydrochloridecas number: 41354-29-4, mol. Formula: c21h22cln, mol.weight: 323.86cyproheptadine hydrochloride is a solid. It is soluble in water (15 mm), chloroform (1:16), methanol (1:1.5), dmso (65 mgml at 25 c), and ethanol (20 mgml at 25 c) with melting point of 165c.Standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Esmolol Hydrochloride

Supplied By UMA Brothers, India

We are offering esmolol hydrochloride is the hydrochloride salt form of esmolol, a short and rapid-acting beta adrenergic antagonist belonging to the class ii anti-arrhythmic drugs and devoid of intrinsic sympathomimetic activity. Esmolol hydrochloride competitively blocks beta-1 adrenergic receptors in cardiac muscle and reduces the contractility and cardiac rate of heart muscle, thereby decreasing cardiac output and myocardial oxygen demands. This agent also decreases sympathetic output centrally and blocks renin secretion. At higher doses, esmolol hydrochloride also blocks beta-2 receptors located in bronchial and vascular smooth muscle, thereby leading to smooth muscle relaxation. synonyms: methyl 3-[4-[2-hydroxy-3-(propan-2-ylamino) propoxy] phenyl] propanoate; hydrochloridecas number: 81161-17-3, mol. Formula: c16h26clno4, mol.weight: 331.83esmolol hydrochloride is a white solid powder. It is soluble in dmso and methanol with melting range of 85c to 86c.Standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Prazosin Hydrochloride

Supplied By UMA Brothers, India

We are offering prazosin hydrochloride is a selective adrenergic alpha-1 antagonist used in the treatment of heart failure; hypertension; pheochromocy- toma raynaud disease; prostatic hypertrophy; and urinary retention. Prazosin hydrochloride is a synthetic piperazine derivative with hypotensive antiadrenergic properties, prazosin hydrochloride reduces peripheral resistance and relaxes vascular smooth muscles as a selective adrenergic alpha-1 antagonist by a mechanism not completely known. It is used in the treatment of heart failure, hypertension, pheochromocytoma, raynaud's syndrome, prostatic hypertrophy, and urinary retention. synonyms: [4-(4-amino-6, 7-dimethoxyquinazolin-2-yl) piperazin-1-yl]-(furan-2-yl) methanone; hydrochloridecas number: 19237-84-4, mol. Formula: c19h22cln5o4, mol.weight: 419.86prazosin hydrochloride is off-white to yellow powder. It is soluble in dmso (36 mm, with sonication), ethanol (5 mm), water (1.4 mgml, about ph 3.5), methanol (6.4 mgml), and dmf (1.3 mgml) with melting range of 277c to 280c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Cytarabine Hydrochloride

Supplied By UMA Brothers, India

We are offering cytarabine hydrochloride.Cytarabine hydrochloride is a pyrimidine nucleoside analog that is used mainly in the treatment of leukemia, especially acute non-lymphoblastic leukemia. Cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of dna. Its actions are specific for the s phase of the cell cycle. It also has antiviral and immunosuppressant properties. Cytarabine hydrochloride is the hydrochloride form of cytarabine, an antimetabolite analogue of cytidine with a modified sugar moiety (arabinose instead of ribose). Cytarabine is converted to the tri- phosphate form within the cell and then competes with cytidine for incorporation into dna. Because the arabinose sugar sterically hinders the rotation of the molecule within dna, dna replication ceases, specifically during the s phase of the cell cycle. This agent also inhibits dna polymerase, resulting in a decrease in dna replication and repair. synonyms: 4-amino-1-[(2r, 3s, 4s, 5r)-3, 4-dihydroxy-5-(hydroxymethyl) oxolan-2-yl] pyrimidin-2-one; hydrochloride cas number: 69-74-9, mol. Formula: c9h14cln3o5, mol.weight: 279.68cytarabine is a white to off-white crystalline powder. It is soluble in water (50 mgml) with melting range of 197c to 198c.Standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Isoxsuprine Hydrochloride

Supplied By UMA Brothers, India

We are offering isoxsuprine hydrochloride.Isoxsuprine hydrochloride is a beta-adrenergic agonist that causes direct relaxation of uterine & vascular smooth muscle. Its vasodilating actions are greater on the arteries supplying skeletal muscle than on those supplying skin. It is used in the treatment of peripheral vascular disease and in premature labor.Isoxsuprine hydrochloride is the hydrochloride salt of isoxsuprine, a benzyl alcohol derivative with vasodilator activity. The mechanism of action of isoxsuprine hydrochloride is controversial because this drug has beta-adrenergic agonist activities that are not reversed by beta-adrenergic blockers. Although stimulation of the beta adrenergic receptor increases blood flow to produce vasodilatation, this drug may also have direct effects on the contractility of smooth muscle. isoxsuprine hydrochloride also causes relaxation of uterine smooth muscle and may also produce positive inotropic and chronotropic effects on the myocardium.Synonyms: 4-[1-hydroxy-2-(1-phenoxypropan-2-ylamino) propyl] phenol; hydrochloridecas number: 579-56-6, mol. Formula: c18h24clno3, mol.weight: 337.84isoxsuprine hydrochloride is a white solid powder. It is soluble in acetone, water with melting range of 203c to 204c.Standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Lercanidipine Hydrochloride

Supplied By UMA Brothers, India

We are offering lercanidipine hydrochloride.Lercanidipine hydrochloride is a calcium channel protein inhibitor which works by relaxing and opening the blood vessels allowing the blood to circulate more freely around the body. It is sold under various commercial names including zanidip. This lowers the blood pressure and allows the heart to work more efficiently. synonyms: 5-o-[1-[3, 3-diphenylpropyl (methyl) amino]-2-methylpropan-2-yl] 3-o-methyl 2, 6-dimethyl-4-(3-nitrophenyl)-1, 4-dihydropyridine-3, 5-dicarboxylate; hydrochloridecas number: 132866-11-6, mol. Formula: c36h42cln3o6, mol.weight: 648.19lercanidipine hydrochloride is a pale-yellow powder. It is soluble in dmso (100 mm), ethanol (10 mm), water (partly), chloroform, and methanol with melting range of 195c to 198c.Standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Hyoscine Hydrochloride

Supplied By UMA Brothers, India

We are offering hyoscine hydrochloride.Hyoscine hydrochloride is also know as -scopolamine hydrochloride. Hyoscine hydrochloride is a competitive nonselective machr m (muscarinic acetylcholine) antagonist. This compound blocks the binding of the acetylcholine ligand and prevents the opening of ion channels. synonyms: hyoscine hydrochloride;scopine tropate hydrochloride; scopine tropate;(-)-scopolamine hydrochloride; scopolamine hydro- chloride;0(sup2, 4))non-7-ylester, hydrochloride, (7(s)-(1-alpha, 2-beta, 4-beta, 5-alpha;5-alpha-h-tropan-3-alpha-ol, 6-beta, 7-beta-epoxy-1-alpha-(-)-tropate(est;chlorhydratedescopolaminecas number: 55-16-3, mol. Formula: c17h22clno4, mol.weight: 339.81hyoscine hydrochloride is a pink to yellow in colour powder. It is soluble in water: 50 mgml.Standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Ticlopidine Hydrochloride

Supplied By UMA Brothers, India

We are offering ticlopidine hydrochloride.Ticlopidine hydrochloride is an effective inhibitor of platelet aggre- gation commonly used in the placement of stents in coronary arteries. Ticlopidine hydrochloride is the hydrochloride salt form of ticlopidine, a thienopyridine derivative with anticoagulant property. Ticlopidine hydrochloride irreversibly inhibits adenosine-diphosphate (adp)-induced platelet-fibrinogen binding by binding to the glycoprotein (gp) iibiiia complex, one of the two purinergic receptors activated by adp. Inhibition of the receptor activation causes the inhibition of adenylyl cyclase, results in decreased levels of cyclic adenosine monophosphate and thereby interferes with platelet membrane function and subsequent, platelet-platelet interaction, release of platelet granule constituents and prolongation of bleeding time. synonyms: 5-[(2-chlorophenyl) methyl]-6, 7-dihydro-4h-thieno [3, 2-c] pyridine; hydrochloridecas number: 53885-35-1, mol. Formula: c14h14clns.clh, mol.weight: 300.25ticlopidine hydrochloride is a white solid powder. It is soluble in methanol, water (4 mgml at 25 c), ethanol (1 mgml at 25 c), and dmso (1 mgml at 25 c) with melting point of 190c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Levofloxacin Hydrochloride

Supplied By UMA Brothers, India

We are offering levofloxacin hydrochloride.Levofloxacin hydrochloride is the hydrochloride salt of levofloxacin (sc-252953), a fluoroquinolone broad spectrum antibiotic with activity against gram-positive and negative bacteria. Levofloxacin is the active s-(-) isomer of the antibacterial agent ofloxacin (sc-219475) and is significantly more efficacious against bacteria than the r-(+) isomer. Levofloxacin & related fluoroquinolones function by inhibiting topo ii (dna gyrase) &topoisomerase iv activity and interrupting dna replication. synonyms: (3s)-9-fluoro-2, 3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7h-pyrido[1, 2, 3-de]-1, 4-benzoxazine-6-carboxylic acid monohydro chloride;7h-pyrido[1, 2, 3-de]-1, 4-benzoxazine-6-carboxylicacid, 9-fluoro-2, 3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, hydrochloride (1:1), (3s)-;3s)-9-fluoro-2, 3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7h-pyrido[1, 2, 3-de]-1, 4-benzoxazine-6-carboxylic acid monohydrochlori cas number: 177325-13-2, mol. Formula: c18h20fn3o4.hcl, mol.weight: 397.83levofloxacin hydrochloride is a crystalline powder. It is soluble in water (25 mgml) with melting range of 220c to 225c.Standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Diphenhydramine

Supplied By UMA Brothers, India

We are offering diphenhydramine. diphenhydramine hcl is white crystalline powder, very soluble in water, freely soluble in alcohol, melting point: 168-172 degree c, ph: 4.0 to 6.0, assay between 99% to 101%. diphenhydramine hcl is is a first-generation antihistamine mainly used to treat allergies. Like most first generation antihistamines, the drug also has a powerful hypnotic effect, and for this reason is often used as a nonprescription sleep aid and a mild anxiolytic. The drug also acts as antiemetic properties which make it useful in treating the nausea that occurs in motion sickness. It is used to treat a number of conditions including allergic symptoms and itchiness , the common cold , insomnia , motion sickness , and extrapyramidal symptoms . Despite being one of the oldest antihistamines, it is more effective than even some of the latest prescription drugs. Consequently, it is frequently used when an allergic reaction requires fast, effective reversal of the often dangerous effects of a massive histamine release. It has sedative properties and is widely used in nonprescription sleep aids. The drug is an ingredient in several products sold as sleep aids, either alone or in combination with other ingredients such as paracetamol. There are also topical formulations of diphenhydramine available, including creams, lotions, gels, and sprays. They are used to relieve itching, and have the advantage of causing much less systemic effect (i.e. Drowsiness) than oral forms. As diphenhydramine is extensively metabolized by the liver , caution should be exercised when giving the drug to individuals with hepatic impairment. diphenhydramine reduces itching that is associated with an allergic reaction, making it a popular choice for treatment of the symptoms of allergic rhinitis , hives , motion sickness , and insect bites and stings. specifications :

diphenhydramine hydrochloride (cas no : 147 24 0)
molecular formula : c17h21no-c1h
molecular weight: 291.85
einecs : 205 -687-2

packing :

diphenhydramine hcl is offered in export worthy 25/50 kg drums

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Metformin Hydrochloride

Supplied By UMA Brothers, India

We are offering metformin hydrochloride. avail from us carefully formulated metformin hydrochloride. The metformin hydrochloride we offer is very high on quality. The metformin hydrochloride is also used in combination with other diabetic drugs. The metformin hydrochloride is carefully formulated under strict supervision of experts. We offer metformin hydrochloride at market leading prices. specifications :

cas no : 1115 - 70 - 4
molecular weight : 165.62
physical form : white or almost white crystalline powder with a scarcely perceptible yellow tinge.
therapeutic cat : anti diabetic
related substances : dicyandiamide 0.02% maximum complies any other impurities 0.1% maximum complies
heavy metals : 10ppm
loss on drying : 0.5% maximum
sulphated ash : 0.1% maximum
assay : 98.54 - 101%
solubility : soluble to 100 mm in water and to 50mm in dmso

biological activity :

antidiabetic agent
lowers plasma glucose levels
improves insulin sensitivity
inhibits hepatic gluconcogenesis via activation of the lkb/ampk pathway
displays antiproliferative effects in cancer cell lines

advantages :

sustained release pellets
lasts long

packing :

25/50 kg export worthy fiber drums or as per our customers choice

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Uma Brothers LBS Marg, Mumbai, Maharashtra

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Verapamil Hydrochloride

Pioglitazone Hydrochloride

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Venlafaxine Hydrochloride

Benazepril Hydrochloride

Doxepin Hydrochloride

Moxifloxacin Hydrochloride

Labetalol Hydrochloride

Ambroxol Hydrochloride

Reserpine Hydrochloride

BETAXOLOL HYDROCHLORIDE

Ranitidine Hydrochloride

Triprolidine Hydrochloride

Sotalol Hydrochloride

Epirubicin Hydrochloride

Dobutamine Hydrochloride

Imipramine Hydrochloride

Naphazoline Hydrochloride

Raloxifene Hydrochloride

Ritodrine Hydrochloride

Tizanidine Hydrochloride

Topotecan Hydrochloride

Trihexyphenidyl Hydrochloride

Ziprasidone Hydrochloride

Bromhexine Hydrochloride

Cyproheptadine Hydrochloride

Esmolol Hydrochloride

Prazosin Hydrochloride

Cytarabine Hydrochloride

Isoxsuprine Hydrochloride

Lercanidipine Hydrochloride

Hyoscine Hydrochloride

Ticlopidine Hydrochloride

Levofloxacin Hydrochloride

Diphenhydramine

Metformin Hydrochloride

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Uma Brothers
LBS Marg, Mumbai, Maharashtra