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Uma Brothers

Uma Brothers
location LBS Marg, Mumbai, Maharashtra

gstGST : 27AGPPS8689E1ZF Verified Write a Review
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Our Products

  1. Medicines Tonics And Drugs 40 Products available
  2. Industrial Acid 38 Products available
  3. Catalysts And Absorbents 20 Products available
  4. Drugs 19 Products available
  5. Pharmaceutical Raw Materials 17 Products available
  6. Industrial Chemicals 15 Products available
  7. Pharmaceutical Chemical 10 Products available
  8. Active Pharmaceutical Ingredients 9 Products available
  9. Api Intermediate 9 Products available
  10. Pharmaceuticals Tablets 8 Products available
  11. Others Products 103 Products available

Active Pharmaceutical Ingredients

We offer a complete product range of HYDROXYZINE DIHYDROCHLORIDE, Indometacin, LOXAPINE, Aztreonam and escitalopram oxalate

Hydroxyzine Dihydrochloride

Hydroxyzine Dihydrochloride
  • Supplied By UMA Brothers, India
Hydroxyzine dihydrochloride is a histamine h1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis and histamine-mediated pruritus. Unlike its major metabolite cetirizine, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative.Hydroxyzine hydrochloride is the hydrochloride salt form of hydroxyzine, a piperazine histamine h1-receptor antagonist with anti-allergic, antispasmodic, sedative, anti-emetic and anti-anxiety properties. Hydroxyzine hydrochloride blocks the h1 histamine receptor and prevents the symptoms that are caused by histamine activity on capillaries, bronchial smooth muscle, and gastrointestinal smooth muscle, including vasodilatation, increased capillary permeability, bronchoconstriction, and spasmodic contraction of gastrointestinal smooth muscle. In addition, hydroxyzine hydrochloride crosses the blood-brain barrier and acts on the histamine h1-receptors in the central nervous system. synonyms: 2-[2-[4-[(4-chlorophenyl)-phenyl methyl] piperazin-1-yl] ethoxy] ethanol; dihydrochloridecas number: 2192-20-3, mol. Formula: c21h29cl3n2o2, mol.weight: 447.83hydroxyzine dihydrochloride is a white solid powder. It is soluble in water (
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Indometacin

Indometacin
  • Supplied By UMA Brothers, India
We are offering indometacin.Indomethacin is a non-steroidal anti-inflammatory agent (nsaid) that inhibits the enzyme cyclooxygenase necessary for the formation of prostaglandins and other autacoids. It also inhibits the motility of polymorphonuclear leukocytes. Indomethacin is a nonsteroidal anti-inflammatory drug. The mechanism of action of indomethacin is as a cyclooxygenase inhibitor. The chemical classification of indomethacin is nonsteroidal anti-inflammatory compounds.Indomethacin is a synthetic nonsteroidal indole derivative with anti-inflammatory activity and chemopreventive properties. As a nonsteroidal anti-inflammatory drug (nsaid), indomethacin inhibits the enzyme cyclooxygenase, thereby preventing cyclooxygenase-mediated dna adduct formation by heterocyclic aromatic amines. This agent also may inhibit the expression of multidrug-resistant protein type 1, resulting in increased efficacies of some antineoplastic agents in treating multi-drug resistant tumors. In addition, indomethacinactivates phosphatases that inhibits the migration and proliferation of cancer cells and downregulates survivin, which may result in tumor cell apoptosis. synonyms: 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl] acetic acidcas number: 53-86-1, mol. Formula: c19h16clno4, mol.weight: 357.79indomethacin is a pale-yellow to yellow-tan, crystalline powder. It is soluble in ethanol, ether, acetone, castor oil; practically insol in water with melting range of 155c to 162c.Standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements
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Loxapine

Loxapine
  • Supplied By UMA Brothers, India
We are offering loxapine is a typical antipsychotic medication, used primarily in the treatment of schizophrenia. Trade names for loxapine taken by mouth include loxapac and loxitane; the inhalable form is approved as adasuve. The drug is a member of the dibenzoxazepineclass and structurally related to clozapine (which belongs to the chemically akin class of dibenzodiazepines). Several researchers have argued that loxapine may behave as an atypical antipsychotic.Loxapine may be metabolized by n-demethylation to amoxapine, a tetracyclic antidepressant. synonyms: 8-chloro-6-(4-methylpiperazin-1-yl) benzo [b] [1, 4] benzoxazepinecas number: 1977-10-2, mol. Formula: c18h18cln3o, mol.weight: 327.80loxapine is a pale yellowish crystals from petroleum ether. It is soluble in water with melting range of 109c to 110c.Standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements
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Aztreonam

Aztreonam
  • Supplied By UMA Brothers, India
We are offering aztreonam.Aztreonam is a monocyclic beta-lactam antibiotic originally isolated from chromobacterium violaceum. It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges, bladder, and kidneys. It may cause a superinfection with gram-positive organisms. Aztreonam is a monobactam antibacterial. The chemical classification of aztreonam is monobactams.Aztreonam is a monocyclic beta-lactam antibiotic originally isolated from chromobacterium violaceum with bactericidal activity. Aztreonam preferentially binds to and inactivatespenicillin-binding protein-3 (pbp-3), which is involved in bacterial cell wall synthesis, thereby inhibiting bacterial cell wall integrity and leading to cell lysis and death. This agent differs from other beta-lactam antibiotics because it is resistant to beta-lactamase hydrolysis, and it is usually used to treat infections caused by gram-negative aerobic microorganisms. synonyms: 2-[(z)-[1-(2-amino-1, 3-thiazol-4-yl)-2-[[(2s, 3s)-2-methyl-4-oxo-1-sulfoazetidin-3-yl]amino]-2-oxoethylidene]amino]oxy-2-methylpropanoic acidcas number: 78110-38-0 mol. Formula: c13h17n5o8s2, mol.weight: 435.43aztreonam is a white crystalline powder. It is soluble in dimethylformamide, dimethyl sulfoxide and water with melting point of 227c.Standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements
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Escitalopram Oxalate

Escitalopram Oxalate
  • Supplied By UMA Brothers, India
We are offering escitalopram oxalate is a furancarbonitrile that is one of the serotonin uptake inhibitors used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from tardive dyskinesia in preference to tricyclic antidepressants, which aggravate this condition.Escitalopram oxalate is the oxalate salt of escitalopram, a pure s-enantiomer of the racemic bicyclic phthalane derivative citalopram, with antidepressant activity. As a selectiveserotonin reuptake inhibitor (ssri), escitalopram blocks the reuptake of serotonin by neurons in the central nervous system (cns), thereby potentiating cns serotonergic activity. synonyms: (1s)-1-[3-(dimethylamino) propyl]-1-(4-fluorophenyl)-3h-2-benzofuran-5-carbonitrile; oxalic acidcas number: 219861-08-2, mol. Formula: c22h23fn2o5, mol.weight: 414.43escitalopram oxalate is a white solid powder. It is soluble in methanol with melting range of 146c to 149c.Standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements
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Roxatidine Acetate

Roxatidine Acetate
  • Supplied By UMA Brothers, India
We are offering roxatidine acetate is a specific and competitive histamine h2 receptor antagonist drug that is used to treat gastric ulcers, zollingerellison syndrome, erosive esophagitis, gastro-oesophageal reflux disease, and gastritis. synonyms: 2-hydroxy-n-[3-[3-(piperidin-1-ylmethyl) phenoxy] propyl] acetamidecas number: 78273-80-0, mol. Formula: c17h26n2o3, mol.weight: 306.4roxatidine is in solid form. It is soluble in water. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements
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Tafluprost

Tafluprost
  • Molar mass 452.5313 g/mol
  • Synonyms (Z)-ISOPROPYL 7-((1r, 2r, 3r, 5s)-2-((E)-3, 3-Difluoro-4-Phenoxybut-1-En-1-Yl)-3, 5-Dihydroxycyclopentyl)
  • Chemical Formula C25H34F2O5
  • Cas Number 209860-87-7
  • Standard Offered in House Specifications
  • Packing Offered in Export Worthy Packing or as per Our Customer Requirements
  • Supplied By UMA Brothers, India

Tafluprost is a prostaglandin analogue. This molecule is used topically for controll of advancing open-angle glaucoma and related problems. It is also used for ocular hypertension, alone or in combination with other molecules. It reduces intraocular pressure by increasing the outflow of aqueous fluid from the eyes.
Chemically, tafluprost is a fluorinated analog of prostaglandin f2-alpha. This chemical compound belongs to the class of organic compounds known as prostaglandins and related compounds.
Tafluprost is light yellow to yellow viscous oil with purity more than 99% by hplc. It is freely soluble in ethanol with melting range of 87.5°c. It is practically insoluble in water.

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Trifluoperazine Dihydrochloride

Trifluoperazine Dihydrochloride
  • Supplied By UMA Brothers, India
We are offering trifluoperazine dihydrochloride is a phenothiazine with actions similar to chlorpromazine. It is used as an antipsychotic and an antiemetic.Trifluoperazine is the hydrochloride salt of trifluoperazine, a pheno- thiazine derivative and a dopamine, alpha-adrenergic & anticholinergic antagonist with antipsychotic, anxiolytic, and antiemetic activities. Trifluoperazine blocks central dopamine receptors, which may prevent or mitigate delusions & hallucinations caused by an excess of dopamine; dopamine blockade in the chemoreceptor trigger zone (ctz) may result in an antiemetic effect. This agent binds to central adrenergic receptors, which may result in anxiolytic effects. trifluoperazine also functions as a calmodulin inhibitor, elevating cytosolic calcium. synonyms: 10-[3-(4-methylpiperazin-1-yl) propyl]-2-(trifluoromethyl) phenothiazine; dihydrochloridecas number: 440-17-5, mol. Formula: c21h26cl2f3n3s, mol.weight: 480.42trifluoperazine dihydrochloride is cream fine powder. It is soluble in water (50 mgml), and methanol (50 mgml- clear, colorless solution) with melting point of 243c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements
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Vardenafil HCL Trihydrate

Vardenafil HCL Trihydrate
  • CAS No. 330808-88-3
  • Purity 98%
  • Supplied By UMA Brothers, India
  • Molecular Formula C23H39ClN6O7S
  • Standard Offered as per in House Specifications
  • Packing Offered in Export Worthy Packing or as per Our Customer Requirements

Vardenafil hydrochloride trihydrate is the hydrochloride salt form of vardenafil, a benzenesulfonamide derivative and phosphodiesterase type 5 (pde5) inhibitor with vasodilatory activity.
Vardenafil is an oral therapy for the treatment of erectile dysfunction. It is a selective inhibitor of cyclic guanosine monophosphate - specific phosphodiesterase type 5 (pde5). During stimulation, nitric oxide is released from nerve endings and endothelial cells in the corpus cavernosum. Nitric oxide activates the enzyme guanylate cyclase resulting in increased synthesis of cyclic guanosine monophosphate (cgmp) in the smooth muscle cells of the corpus cavernosum. The cgmp in turn triggers smooth muscle relaxation, allowing increased blood flow. Therefore, the inhibition of pde5 enhances erectile function by increasing the amount of cgmp.

Iupac name : 2-2-ethoxy-5-[(4-ethylpiperazin-1-yl)sulfonyl] phenyl-5-methyl-7-propyl-1h, 4h-imidazo[4, 3-f][1, 2, 4]triazin-4-one trihydrate hydrochloride
Vardenafil hydrochloride trihydrate is white powder with assay more than 99% by hplc (anhydrous substance). It is slightly solube in water, freely soluble in anhydrous ethanol & practicaly insoluble in heptane.

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