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UMA Brothers

UMA Brothers
Mumbai, Maharashtra

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Pharmaceutical Medicine

We are leaders in the market for providing best range of Enalapril, Lamotrigine, Sumatriptan, Timolol and peptidyl dipeptidase inhibitor

Enalapril

Enalapril
  • Min. Order (MOQ) 25 Kilogram
  • WHITE POWDER WHITE POWDER
Enalapril is an angiotensin-converting enzyme inhibitor that is used to treat hypertension and heart failure. Enalapril is an angiotensin converting enzyme inhibitor. The mechanism of action of enalapril is as an angiotensin-converting enzyme inhibitor. The physiologic effect of enalapril is by means of decreased blood pressure.Enalapril maleate is the maleate salt form of enalapril, a dicarbocyl-containing peptide and angiotensin-converting enzyme (ace) inhibitor with antihypertensive activity. As a prodrug, enalapril is converted by de-esterification into its active form enalaprilat. Enalaprilat competitively binds to and inhibits ace, thereby blocking the conversion of angiotensin ito angiotensin ii. This prevents the potent vasoconstrictive actions of angiotensin ii and results in vasodilation. Enalapril also decreases angiotensin ii-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow.
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Lamotrigine

Lamotrigine
  • Min. Order (MOQ) 25 Kilogram
  • WHITE TO CREAM COLOURED POWDER WHITE TO CREAM COLOURED POWDER
Lamotrigine is an anti-epileptic agent and mood stabilizer. The physiologic effect of lamotrigine is by means of decreased central nervous system disorganized electrical activity.Lamotrigine is a synthetic phenyltriazine with antiepileptic and analgesic properties. Lamotrigine enhances the action of gamma-aminobutyric acid, an inhibitory neurotransmitter, which may result in a reduction of pain-related transmission of signals along nerve fibers. This agent may also inhibit voltage-gated sodium channels, suppress glutamate release, and inhibit serotonin reuptake.
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Sumatriptan

Sumatriptan
  • Min. Order (MOQ) 25 Kilogram
  • WHITE CRYSTALLINE SOLID OR POWDER WHITE CRYSTALLINE SOLID OR POWDER
Sumatriptan is a serotonin agonist that acts selectively at 5ht1 receptors. It is used in the treatment of migraine disorders. Sumatriptan is a serotonin-1b and serotonin-1d receptor agonist. The mechanism of action of sumatriptan is as a serotonin 1b receptor agonist & serotonin 1d receptor agonist.Sumatriptan is a sulfonamide triptan with vasoconstrictor activity. sumatriptan selectively binds to & activates serotonin 5-ht1d receptors in the central nervous system (cns), thereby constricting cerebral blood vessels. This may lead to a relief in pain from vascular headaches. Sumatriptan may also relieve vascular headaches by decreasing the release of vasoactive neuropeptides from perivascular trigeminal axons in the dura mater during a migraine, by reducing extravasation of plasma proteins, and by decreasing the release of other mediators of inflammation from the trigeminal nerve.
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Timolol

Timolol
  • Min. Order (MOQ) 25 Kilogram
  • WHITE SOLID POWDER WHITE SOLID POWDER
Timolol anhydrous is a beta-adrenergic blocker. The mechanism of action of timolol anhydrous is as an adrenergic beta-antagonist. A beta-adrenergic antagonist similar in action to propranolol.the levo-isomer is the more active. Timolol has been proposed as an antihyper- tensive, antiarrhythmic, antiangina, and antiglaucoma agent. It is also used in the treatment of migraine disorders and tremor.
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peptidyl dipeptidase inhibitor

Peptidyl Dipeptidase Inhibitor
  • Min. Order (MOQ) 25 Kilogram
  • WHITE TO OFF-WHITE, CRYSTALLINE POWDER WHITE TO OFF-WHITE, CRYSTALLINE POWDER

A potent and specific inhibitor of peptidyl-dipeptidase a. It blocks the conversion of angiotensin I to angiotensin ii, a vasoconstrictor and important regulator of arterial blood pressure. Captopril acts to suppress the renin-angiotensin system and inhibits pressure responses to exogenous angiotensin. Captopril is an angiotensin converting enzyme inhibitor. The mechanism of action of captopril is as an angiotensin-converting enzyme inhibitor. Captopril is a sulfhydryl-containing analog of proline with antihypertensive activity and potential antineoplastic activity. Captopril competitively inhibits angiotensin converting enzyme (ace), thereby decreasing levels of angiotensin ii, increasing plasma renin activity, and decreasing aldosterone secretion. This agent may also inhibit tumor angiogenesis by inhibiting endothelial cell matrix metalloproteinases (mmps) and endothelial cell migration. Captopril may also exhibit antineoplastic activity independent of effects on tumor angiogenesis.

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