UMA Brothers

Mumbai, Maharashtra

Celecoxib is A cox-2 Selective nonsteroidal Anti-inflammatory Drug   (nsaid). It is Used to Treat the Pain and Inflammation of Osteoarthritis, Rheumatoid Arthritis, ankylosing Spondylitis, acute Pain in Adults, Painful menstruation, and Juvenile Rheumatoid Arthritis. Celecoxib is Used For reduce the Number of Colon and Rectal Polyps in People With familial Adenomatous Polyposis. for Postoperative Pain, It is More or Less Equal To ibuprofen. for Pain Relief, It is Similar to Paracetamol  (acetaminophen). and in Osteoarthritis Acetaminophen is the First Line Treatment for Oa. It is Originally Intended to Relieve Pain While Minimizing Gastrointestinal Adverse Effects Seen with Conventional Nsaids. in Practice, Its Primary Use is in People Who Need Regular and Long-term Pain Relief; Probably, No Advantage Exists to Using Celecoxib for Short-term or Acute Pain Relief Over Conventional Nsaids, Except in the Situation Where Nonselective Nsaids or Aspirin Cause Cutaneous Reactions (urticaria or "hives").

 

Details :

• Synonyms - 4-[5-(4-methylphenyl)-3-(trifluoromethyl) Pyrazol-1-yl] Benzenesulfonamide
• Cas Number - 169590-42-5.
• Mol. Formula - C17h14f3n3o2s.
• Mol. Weight - 381.37.
• It is Yellow Crystalline Powder, Soluble to 25 Mm in Dmso and to 50 Mm in Ethanol and Very Low water solubility with Its Melting Point of 157°C to 158°C.

Flurbiprofen is Used to Treat the Inflammation and Pain Of arthritis. Flurbiprofen is a Derivative Of propionic Acid, and a Phenylalkanoic Acid Derivative of Non-steroidal Antiinflammatory Drugs (nsaids) with Analgesic, Antiinflammatory and Antipyretic Effects. flurbiprofen non-selectively Binds to and Inhibits Cyclooxygenase (cox). this Results in a Reduction Of arachidonic Acid conversion Into Prostaglandins that are Involved in the Regulation of Pain, Inflammation and Fever. this Nsaid also Inhibits Carbonic Anhydrase, Thereby Reducing the Production of Hydrogen & Bicarbonate Ions. Upon Ocular Administration, flurbiprofen May Reduce bicarbonate ion Concentrations Leading to a Decrease in the Production of Aqueous Humor, Thereby Lowering Intraocular Pressure. Flurbiprofen is An Nsaid Which Treats the Symptoms of Inflammation and Pain. They Do Not Treat the Disease that Causes Those Symptoms.

Details

• Synonyms - 2-fluoro-alpha-methyl-(1, 1'-biphenyl)-4-acetic Acid
• Cas Nunber - 51543-40-9
• Molecular Formula - C15h13fo2
• Molecular Weight - 244.26
• It is in Powder Form with Melting Range: 110°C to 111°C. It is Available as Flurbiprofen Sodium and Flurbiprofen Axetil.
• Standard - Offered of Pharmaceutical Grade BP/USP/EP
• Packing - Offered in Export Worthy Packing of 25 Kilos or as per Our Customer Requirements.

Irbesartan Is An Angiotensin Ii Receptor Antagonist Used Mainly For The Treatment Of Hypertension. It Is Used For High Blood Pressure Alone Or With Other Medicines. It Is Also Used In Certain Patients To Treat Kidney Problems Caused By Diabetes (Diabetic Nephropathy). Irbesartan Is An Angiotensin Ii Receptor Blocker (Arb). It Works By Relaxing Blood Vessels To Lower Blood Pressure. The Renin-angiotensin System Plays An Important Role In The Regulation Of Blood Volume And Blood Pressure, Stimulates Antidiuretic Hormone and Aldosterone Production, And The Hypothalamus To Activate The Thirst Reflex, But Is Crucial In The Pathogenesis Of Hypertension Patients Due To Blood Vessels Constrict, Retention Of Fluid And Raising Blood Pressure. Ace Inhibitors Prevent A.i From Converting Into A.ii. And Act To Widen The Blood Vessels And Make It Easier For The Heart To Pump Blood Through The Body. They Prevent From Cardiovascular Disorders, Left Ventricular Dysfunction, And Nephropathy In Diabetes Mellitus. They Also Helps Control The Amount Of Blood In Your Body.

Details

• Synonyms - 2-n-butyl-3-((2'-(1h-tetrazol-5-yl) Biphenyl-4-yl) Methyl)-1, 3-diazaspiro(4, 4) Non-1-en-4-one
• Cas Number - 138402-11-6
• Mol.Weight - 428.52
• Molecular Formula - C25h28n6o
• It Is Available In White Crystalline Powder With Melting Range 180-181 °C.
• Standard - Offered Of Pharmaceutical Grade BP/USP/EP
• Packing - Offered In Export Worthy Packing Of 25 Kilos Or As Per Our Customer Requirements

Carvedilol is a Synthetic Antihypertensive Methoxyphenoxy- 2-propanol Derivative with No Intrinsic Sympathomimetic Activity, carvedilol acts as a Nonselective Beta-adrenoceptor Blocking Agent (s(-) Enantiomer) and as An Alpha 1-adrenoceptor Blocker (r(+) and S(-) Enantiomers). Carvedilol is a Beta-blocker Which Affects the Heart and Circulation (blood Flow Through Arteries and Veins). Carvedilol is Used to Treat Heart Failure and Hypertension (high Blood Pressure). It is also Used After a Heart Attack that Has Caused Your Heart Not to Pump as Well. Carvedilol is A nonselective Beta Blocker/alpha-1 Blocker used in the Treatment of Mild to Severe congestive Heart Failure (chf). It Has a Significant Role in the Treatment of Congestive Heart Failure.

 

Details :

• Synonyms - 1-(9h-carbazol-4-yloxy)-3-[2-(2-methoxy Phenoxy) Ethylamino] Propan-2-ol
• Cas Number - 72956-09-3
• Mol Formula - C24h26n2o4
• Mol. Weight: 406.5
• It is a White to Off-white Powder with Its Melting Range of 113 °C- 117 °c. It is Freely Soluble in Dimethylsulfoxide; Soluble in Methylene Chloride and Methanol; Sparingly Soluble in 95% Ethanol and Isopropanol; Slightly Soluble in Ethyl Ether; and Practically Insoluble in Water.
• Standard - Offered of Pharmaceutical Grade BP/USP/EP
• Packing - Offered in Export Worthy Packing of 25 Kilos or as per Our Customer Requirements.

Anti-inflammatory Painkillers like Etoricoxib are Sometimes Called Non-steroidal Anti-inflammatory Drugs (nsaids), or Just 'anti-inflammatories'. Etoricoxib is Used to Treat Painful Conditions such As arthritis, gout and Dental Pain After Surgery. It Eases Pain and Reduces Inflammation. Etoricoxib is also Known as a Cyclo-oxygenase-2 Inhibitor. this is Because It Works to Relieve Pain and Inflammation By Blocking An Enzyme in the Body Called Cyclo-oxygenase-2 (cox-2). Cox-2 is Involved in the Production of Irritant Substances in the Body in Response to Disease and Injury. By Blocking the Action of Cox-2, Etoricoxib Reduces the Symptoms of Pain and Inflammation.

Details

• Synonyms - 5-chloro-6'-methyl-3-[4-(methylsulfonyl) Phenyl]-2, 3'-bipyridine, Algix, Arcoxia, Etobrix, Etocox.
• Cas Number - 202409-33-4
• Mol. Formula - C18h15cln2o2s
• Mol. Weight - 358.84
• It is a White to Off-white Powder. Etoricoxib is Freely Soluble in Methanol, Tetrahydrofuran, Dimethyl Sulfoxide, Methyl Ethyl Ketone, Dimethyl Formamide, and Chloroform with Its Melting Range Of 134 ºC -135ºC
• Standard - Offered of Pharmaceutical Grade BP/USP/EP.
• Packing - Offered in Export Worthy Packing of 25 Kilos or as per Our Customer Requirements.

Terlipressin acetate is an analogue of vasopressin used as a vasoactive for proteomics research. It has been found to be effective when norepinephrine is not.

Silver sulfadiazine is a sulfonamide antibacterial. Sulfadiazine silver is a sulfonamide-based topical agent with antibacterial & antifungal activity. Silver sulfadiazine may act through a combination of the activity of silver & sulfadiazine. When this agent interacts with sodium chloride-containing body fluids, silver ions are released slowly and sustainably into wounded areas. Ionized silver atoms catalyze the formation of disulfide bonds leading to protein structural changes and inactivating thiol-containing enzymes; silver ions may also intercalate dna thereby interfering with replication and transcription of bacteria. As a competitive inhibitor of para-aminobenzoic acid (paba), sulfadiazine inhibits bacterial dihydropteroate synthase, thereby resulting in disruption of folic acid metabolism and ultimately dna synthesis.

Sildenafil Citrate Is The Citrate Salt Of A Pyrazolo Pyrimidinone Derivative Structurally Related To Zaprinast. Sildenafil Citrate Is A Phosphodiesterase Type-5 Inhibitor, Vasodilator Agent And Urological Agent That Is Used In The Treatment Of Erectile Dysfunction And Primary Pulmonary Hypertension. sildenafil Selectively Inhibits Cyclic Guanosine Monophosphate (Cgmp)-specific Type 5 Phosphodiesterase, Resulting In Vasodilation In The Corpus Cavernosum Of The Penis And Penile Erection. It Relaxes The Arterial Wall, Leading To Decreased Pulmonary Arterial Resistance And Pressure. This, In Turn, Reduces The Workload Of The Right Ventricle Of The Heart And Improves Symptoms Of Right-sided Heart Failure.it Works By Relaxing And Dilating The Blood Vessels In The Lungs. This Lowers The Blood Pressure In The Lungs And Helps To Improve Your Ability To Exercise.

Details

• Synonyms - 1-((3-(6, 7-dihydro-1-methyl-7-oxo-3-propyl-1h-pyrazolo (4, 3-d) Pyrimidin-5-yl)-4-ethoxyphenyl) Sulfonyl)-4-methylpiperazine                       
• Cas Number - 171599-83-0
• Mol.formula - C28h38n6o11s
• Mol. Weight - 666.69   
• It Is Whte Colour Powder With Melting Point Of 187°c. It Is Soluble In Water And Dmso.
• Standard - Offered Of Pharmaceutical Grade BP/USP/EP
• Packing - Offered In Export Worthy Packing Of 25 Kilos Or As Per Our Customer Requirements.

Albendazole is a benzimidazole broad-spectrum anthelmintic structurally related to mebendazole that is effective against many diseases. It is used for the treatment of a variety of parasitic worm infestations. It is useful for giardiasis, trichuriasis, filariasis, neurocysticercosis, hydatid disease, pinworm disease, and ascariasis, among others. Albendazole is an antihelminthic. Albendazole is a broad-spectrum, synthetic benzimidazole-derivative anthelmintic. Albendazole interferes with the reproduction and survival of helminths by inhibiting the formation of microtubules from tubulin. This leads to an impaired uptake of glucose, a depletion of glycogen stores, and results in the worm's death. Albendazole is used in the treatment of dog and pork tapeworm-causing diseases, including hydatid disease and neurocysticercosis. Albendazole may also be used to treat a variety of other roundworm infections. Albendazole is an anthelmintic or anti-worm medication. It prevents newly hatched insect larvae (worms) from growing or multiplying in the body.

Propyphenazone is an analgesic, antipyretic, and anti-inflammatory.Synonyms: 1, 5-dimethyl-2-phenyl-4-propan-2-ylpyrazol-3-one

Zinc oxide is a mild astringent and topical protectant with some antiseptic action. It is also used in bandages, pastes, ointments, dental cements, and as a sunblock. Crude zinc oxide is a yellow-gray granular solid with no odor. It is insoluble in water. The primary hazard is the threat posed to the environment. Immediate steps should be taken to limit its spread to the environment. Prolonged inhalation of the dust may result in metal fume fever with symptoms of chills, fever, muscular pain, nausea and vomiting.

Aluminium hydroxide, aloh3, is found in nature as the mineral gibbsite (also known as hydrargillite) and its three much rarerpolymorphs: bayerite, doyleite and nordstrandite. Closely related are aluminium oxide hydroxide, al2oh, and aluminium oxide (or alumina), al2o3. These compounds together are the major components of the aluminium ore bauxite. Freshly precipitated aluminium hydroxide forms gels, which are the basis for the application of aluminium salts as flocculants in water purification. This gel crystallizes with time. Aluminium hydroxide gels can be dehydrated (e.g. Using water-miscible non-aqueous solvents likeethanol) to form an amorphous aluminium hydroxide powder, which is readily soluble in acids. Aluminium hydroxide powder which has been heated to an elevated temperature under carefully controlled conditions is known as activated alumina and is used as adesiccant, as an adsorbent in gas purification, as a claus catalyst support for water purification, and as an adsorbent for the catalyst during the manufacture of polyethylene by the sclairtech process. synonyms: hydroxy (oxo) alumane, cas number: 21645-51-2 mol. Formula: aloh3, mol.weight: 78.00

Carboplatin is an organoplatinum compound that possesses antineoplastic activity.Carboplatin is a second-generation platinum compound with a broad spectrum of antineoplastic properties. Carboplatin contains a platinum atom complexed with two ammoniagroups and a cyclobutane-dicarboxyl residue. This agent is activated intracellularly to form reactive platinum complexes that bind to nucleophilic groups such as gc-rich sites in dna, thereby inducing intrastrand and interstrand dna cross-links, as well as dna-protein cross-links. These carboplatin-induced dna and protein effects result in apoptosis and cell growth inhibition. This agent possesses tumoricidal activity similar to that of its parent compound, cisplatin, but is more stable and less toxic.

Zinc gluconate (also called zincum gluconicum) is the zinc salt of gluconic acid. It is an ionic compound consisting of two moles of gluconate for each mole of zinc. Zinc gluconate is a popular form for the delivery of zinc as a dietary supplement.

Ofloxacin is a synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial dna gyrase, halting dna replication. Ofloxacin is a racemic mixture, which consists of 50% levofloxacin (the biologically active component) and 50% of its mirror image or enantiomer dextrofloxacin. Ofloxacin has been associated with adverse drug reactions, such as tendon damage (including spontaneous tendon ruptures) andperipheral neuropathy (which may be irreversible); tendon damage may manifest long after therapy had been completed, and, in severe cases, may result in lifelong disabilities.

Betamethasone is a corticosteroid. The mechanism of action of betamethasone is as a corticosteroid hormone receptor agonist. Betamethasone is a synthetic glucocorticoid with metabolic, immunosuppressive and anti-inflammatory activities. Betamethasone binds to specific intracellular glucocorticoid receptors and subsequently binds to dna to modify gene expression. The synthesis of certain anti-inflammatory proteins is induced while the synthesis of certain inflammatory mediators is inhibited. As a result, there is an overall reduction in chronic inflammation and autoimmune reactions.a glucocorticoid given orally, parenterally, by local injection, by inhalation, or applied topically in the management of various disorders in which corticosteroids are indicated. Its lack of mineralocorticoid properties makes betamethasone particularly suitable for treating cerebral edema and congenital adrenal hyperplasia.