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Post Buy Requirement
UMA Brothers

UMA Brothers
Mumbai, Maharashtra

gstGST : 27AGPPS8689E1ZF Verified Add Review
Call 08047020551

Our Products

  1. Medicines Tonics And Drugs 30 Products available
  2. Industrial Acid 29 Products available
  3. Industrial Chemicals 16 Products available
  4. Drugs 15 Products available
  5. Catalysts And Absorbents 13 Products available
  6. Pharmaceutical Raw Materials 11 Products available
  7. Pharmaceutical Chemical 8 Products available
  8. Api Intermediate 8 Products available
  9. Pharmaceuticals Tablets 6 Products available
  10. Pharmaceutical Medicine 5 Products available
  11. Others Products 118 Products available

Api Intermediate

We are leaders in the market for providing best range of Pharmaceutical Intermediates, Colchicine, Guaifenesin, Indapamide and Doxazosin Mesylate

pharmaceutical intermediates

Pharmaceutical Intermediates
  • Form Liquid, Powder etc.
  • Purity 99%
  • Storage Cool & Dry Place
  • Shelf Life 1 Year
  • Usage Industrial
  • Grade Parma

Ntermediates For Apis, Bulk Drugs & Pharmaceutical Raw Materials.

  • 4 Nitro 2, 3 Dimethyl Pyridine 1 Oxide
  • 2(Hydroxy Methyl) 3 Methyl 4 (2, 2, 2 Trifluoro Ethoxy) Pyridine Hydrochloride
  • 2 Chloromethyl 3 Methyl 4 (2, 2, 2 Trifluoro Ethoxy) Pyridine Hydrochloride
  • 2[[[3methyl 4 (2, 2, 2 Trifluoro Ethoxy) 2 Pyridinyl] Methyl] Sulfanyl] 1h Benzimidazole
  • 5 Methoxy 3h Imidazo [4, 5 B] Pyridine 2 Thiol
  • 2(3, 5 Dimethyl 4 Nitro Pyridine 2 Ylmethylsulfanyl) 5 Methoxy 1h Benzoimidazole
  • 2 Chloromethyl 3 Methyl 4 Methoxypyridine Hydrochloride
  • 1 (2, 4 Dichlorophenyl) 2 (1h Imidazol 1 Yl) Ethanol
  • 1(4 Chloro Phenyl) N Formyl Alpha (2 Methyl Propyl) Cyclo Butane Methanamine
  • (S) 3 (Methylamino) 1 (Thiophen 2 Yl) Propan 1 Ol
  • 1 [2(2 Hydroxy Ethoxy) Ethyl] Piperazine
  • 6 Hydroxy 3, 4 Dihydro Quinolinone
  • 4 Hydroxy, 2 Methyl, 2h, 1, 2 Benzothiazine Carboxylic Acid Isopropyl Ester 1, 1 Dioxide
  • 2 Amino 5 Methyl Thiazole
  • 1(3 Dimethylaminopropyl) 3 Ethylcarbodiimide Hcl
  • 3 Hydroxy Acetophenone
  • 1(6 Methylpyridine 3yl) 2[(4(Methylsulphonyl) Phenyl] Ethanol [ketosulfone]
  • 2 Butyl 4 Chloro 5 Formylimidazole Or Bcfi
  • 4 Methylbiphenyl 2 Carboxylic Acid Methyl Ester
  • (±) 3 (Carbamoyl Methyl) 5 Methyl Hexanoic Acid
  • 1[2(2 Hydroxy) Ethyl] Piperazine
  • 2, 4, 5 Trifluorophenyl Acetic Acid
  • 3 Amino 4 Pyrazolecarboxamide Hemisulfate
  • S (-) N, N Dimethyl 3 Hydroxy 3(2 Thienyl) Propanamine
  • Packing - Offered In Export Worthy Packing
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Colchicine

Colchicine
  • Min. Order (MOQ) 25 Kilogram
  • PALE YELLOW SCALES OR POWDER PALE YELLOW SCALES OR POWDER
Colchicine is a major alkaloid from colchicum autumnale l. And found also in other colchicum species. Its primary therapeutic use is in the treatment of gout, but it has been used also in the therapy of familial mediterranean fever (periodic disease). The mechanism of action of colchicine is as a cytochrome p450 3a4 inhibitor and p-glycoprotein interaction.Colchicine is an alkaloid isolated from colchicum autumnale with anti-gout and anti-inflammatory activities. The exact mechanism of action by which colchicines exerts its effect has not been completely established. Colchicine binds to tubulin, thereby interfering with the polymerization of tubulin, interrupting microtubule dynamics, and disrupting mitosis. This leads to an inhibition of migration of leukocytes and other inflam- matory cells, thereby reducing the inflammatory response to deposited urate crystals. Colchicine may also interrupt the cycle of monosodium urate crystal deposition in joint tissues, thereby also preventing the resultant inflammatory response. Overall, colchicine decreases leuko- cyte chemotaxismigration and phagocytosis to inflamed areas, and inhibits the formation and release of a chemotactic glycoprotein that is produced during phagocytosis of uratecrystals.
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Guaifenesin

Guaifenesin
  • Min. Order (MOQ) 25 Kilogram
  • WHITE CRYSTALLINE POWDER WHITE CRYSTALLINE POWDER
guaifenesin is an expectorant that also has some muscle relaxing action. it is used in many cough preparations.guaifenesin is a glyceryl guaiacolate with expectorant effects. guaifenesin increases respiratory tract mucus secretions, acts as an irritant to gastric vagal receptors and recruits efferent parasym- pathetic reflexes that cause glandular exocytosis. this agent reduces the viscosity of mucus secretion by reducing adhesiveness and surface tension as well as increasing hydration of mucus.guaifenesin promotes the efficiency of the mucociliary mechanism important in removing accumulated secretions from the upper and lower airway.
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Indapamide

Indapamide
  • Min. Order (MOQ) 25 Kilogram
  • WHITE CRYSTALLINE SOLID POWDER WHITE CRYSTALLINE SOLID POWDER
Indapamide is a benzamide-sulfonamide-indole derived diuretic that functions by inhibiting sodium chloride symporters.Indapamide is an indole derivative of chlorosulphonamide and a sulfamyl diuretic with antihypertensive activity. Indapamide may interact directly with the subunits of delayed rectifierpotassium channels, thereby blocking both slow and rapid k+ (iks and ikr) currents through the channels. Through the homeostasis mechanism in balancing total ion concentration (ca++, na+), it reduces vascular hyperreactivity and peripheral and arterial vascular resistance, possibly by inhibiting transmembrane ionic influx, probably calcium ions, and stimulating prostaglandin e2 synthesis, thereby causing vasodilatation. Indapamide exerts its diuretic effect by inhibiting reabsorption of sodium and chloride, primarily as a result of action on the cortical diluting segment of the renal distal tubule, thereby promoting urinary excretion of water and electrolytes.
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Doxazosin Mesylate

Doxazosin Mesylate
  • Min. Order (MOQ) 25 Kilogram
  • WHITE CRYSTALLINE POWDER WHITE CRYSTALLINE POWDER
Doxazosin mesylate is a prazosin-related compound that is a selective alpha-1-adrenergic blocker.Doxazosin mesylate is the mesylate salt form of doxazosin, a quinazoline compound with smooth muscle relaxing activity. Doxazosin mesylate selectively antagonizes alpha-1-adrenergic receptors in smooth muscle of the bladder neck and prostate, thereby relaxing the smooth muscle and decreasing the obstruction and urethral resistance seen with benign prostate hyperplasia (bph). This may improve bph symptoms. This agent also blocks alpha-1-adrenergic receptors in peripheral vascular smooth muscle, which leads to vasodilatation and a subsequent decrease in peripheral vascular resistance.
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pentoxifylline

Pentoxifylline
  • Min. Order (MOQ) 25 Kilogram
  • WHITE TO OFF-WHITE SOLID POWDER WHITE TO OFF-WHITE SOLID POWDER
Pentoxifylline is a methylxanthine derivative with hemorrheologic & immunomodulating properties. Pentoxifylline inhibits phosphodiesterase, resulting in increased levels of cyclic adenosine monophosphate (camp) in erythrocytes, endothelium & the surrounding tissues. This leads to vasodilation, improves erythrocyte flexibility & enhances blood flow. In addition the increased level of camp in platelets inhibits platelet aggre- gation which may contribute to a reduction in blood viscosity. This agent also inhibits production of tumor necrosis factor-alpha & inter- feron-gamma while it induces th2-like (t-helper 2) cytokine production, thereby inhibiting th1-mediated (t-helper 1) inflammatory & autoimmune responses.Pentoxifylline is a blood viscosity reducer. The physiologic effect of it is by means of hematologic activity alteration. Threfore, methy lxanthine derivative that inhibits phosphodiesterase & affects blood rheology. It improves blood flow by increasing erythrocyte & leukocyte flexibility. It also inhibits platelet aggregation. Pentoxi fylline modulates immunologic activity by stimulating cytokine production.
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Simvastatin

Simvastatin
  • Min. Order (MOQ) 25 Kilogram
  • WHITE SOLID POWDER WHITE SOLID POWDER
Simvastatin is a derivative of lovastatin and potent competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme a reductase (hydroxy methylglutaryl coa reductases), which is the rate-limiting enzyme in cholesterol biosynthesis. It may also interfere with steroid hormone production. Due to the induction of hepatic ldl receptors, it increases breakdown of ldl cholesterol. Simvastatin is a hmg-coa reductase inhibitor. The mechanism of action of simvastatin is as a hydroxy methylglutaryl-coa reductase inhibitor.Simvastatin is a lipid-lowering agent derived synthetically from a fermentation product of the fungus aspergillus terreus. Hydrolyzed in vivo to an active metabolite, simvastatincompetitively inhibits hepatic hydroxymethyl-glutaryl coenzyme a (hmg-coa) reductase, the enzyme which catalyzes the conversion of hmg-coa to mevalonate, a key step incholesterol synthesis. This agent lowers plasma cholesterol and lipoprotein levels, and modulates immune responses by suppressing mhc ii (major histocompatibility complex ii) on interferon gamma-stimulated, antigen-presenting cells such as human vascular endothelial cells.
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Candesartan

Candesartan
  • Min. Order (MOQ) 25 Kilogram
  • COLOURLESS CRYSTALLINE SOLID POWDER COLOURLESS CRYSTALLINE SOLID POWDER
Candesartan is an angiotensin 2 receptor blocker. The mechanism of action of candesartan is as an angiotensin 2 receptor antagonist.Candesartan is a synthetic, benzimidazole-derived angiotensin ii receptor antagonist prodrug with antihypertensive activity. candesartan selectively competes with angiotensin ii for the binding of the angiotensin ii receptor subtype 1 (at1) in vascular smooth muscle, blocking angiotensin ii-mediated vasoconstriction and inducing vasodilatation. In addition, antagonism of at1 in the adrenal gland inhibits angiotensin ii-stimulated aldosterone synthesis and secretion by the adrenal cortex; sodium and water excretion increase, followed by a reduction in plasma volume and blood pressure.
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Retailer of Api Intermediate from Mumbai, Maharashtra by UMA Brothers
Product / Services
Post Buy Requirement
UMA Brothers

UMA Brothers
Mumbai, Maharashtra

gstGST : 27AGPPS8689E1ZF Verified Add Review
Call 08047020551

Our Products

  1. Medicines Tonics And Drugs 30 Products available
  2. Industrial Acid 29 Products available
  3. Industrial Chemicals 16 Products available
  4. Drugs 15 Products available
  5. Catalysts And Absorbents 13 Products available
  6. Pharmaceutical Raw Materials 11 Products available
  7. Pharmaceutical Chemical 8 Products available
  8. Api Intermediate 8 Products available
  9. Pharmaceuticals Tablets 6 Products available
  10. Pharmaceutical Medicine 5 Products available
  11. Others Products 59 Products available

Api Intermediate

Our Complete range of products are Pharmaceutical Intermediates, Colchicine, Guaifenesin, Indapamide and Doxazosin Mesylate.

pharmaceutical intermediates

Pharmaceutical Intermediates
  • Form Liquid, Powder etc.
  • Purity 99%
  • Storage Cool & Dry Place
  • Shelf Life 1 Year
  • Usage Industrial
  • Grade Parma

Ntermediates For Apis, Bulk Drugs & Pharmaceutical Raw Materials.

  • 4 Nitro 2, 3 Dimethyl Pyridine 1 Oxide
  • 2(Hydroxy Methyl) 3 Methyl 4 (2, 2, 2 Trifluoro Ethoxy) Pyridine Hydrochloride
  • 2 Chloromethyl 3 Methyl 4 (2, 2, 2 Trifluoro Ethoxy) Pyridine Hydrochloride
  • 2[[[3methyl 4 (2, 2, 2 Trifluoro Ethoxy) 2 Pyridinyl] Methyl] Sulfanyl] 1h Benzimidazole
  • 5 Methoxy 3h Imidazo [4, 5 B] Pyridine 2 Thiol
  • 2(3, 5 Dimethyl 4 Nitro Pyridine 2 Ylmethylsulfanyl) 5 Methoxy 1h Benzoimidazole
  • 2 Chloromethyl 3 Methyl 4 Methoxypyridine Hydrochloride
  • 1 (2, 4 Dichlorophenyl) 2 (1h Imidazol 1 Yl) Ethanol
  • 1(4 Chloro Phenyl) N Formyl Alpha (2 Methyl Propyl) Cyclo Butane Methanamine
  • (S) 3 (Methylamino) 1 (Thiophen 2 Yl) Propan 1 Ol
  • 1 [2(2 Hydroxy Ethoxy) Ethyl] Piperazine
  • 6 Hydroxy 3, 4 Dihydro Quinolinone
  • 4 Hydroxy, 2 Methyl, 2h, 1, 2 Benzothiazine Carboxylic Acid Isopropyl Ester 1, 1 Dioxide
  • 2 Amino 5 Methyl Thiazole
  • 1(3 Dimethylaminopropyl) 3 Ethylcarbodiimide Hcl
  • 3 Hydroxy Acetophenone
  • 1(6 Methylpyridine 3yl) 2[(4(Methylsulphonyl) Phenyl] Ethanol [ketosulfone]
  • 2 Butyl 4 Chloro 5 Formylimidazole Or Bcfi
  • 4 Methylbiphenyl 2 Carboxylic Acid Methyl Ester
  • (±) 3 (Carbamoyl Methyl) 5 Methyl Hexanoic Acid
  • 1[2(2 Hydroxy) Ethyl] Piperazine
  • 2, 4, 5 Trifluorophenyl Acetic Acid
  • 3 Amino 4 Pyrazolecarboxamide Hemisulfate
  • S (-) N, N Dimethyl 3 Hydroxy 3(2 Thienyl) Propanamine
  • Packing - Offered In Export Worthy Packing
View Complete Details
Ask Latest Price & Details
Colchicine

Colchicine
  • Min. Order (MOQ) 25 Kilogram
  • PALE YELLOW SCALES OR POWDER PALE YELLOW SCALES OR POWDER
Colchicine is a major alkaloid from colchicum autumnale l. And found also in other colchicum species. Its primary therapeutic use is in the treatment of gout, but it has been used also in the therapy of familial mediterranean fever (periodic disease). The mechanism of action of colchicine is as a cytochrome p450 3a4 inhibitor and p-glycoprotein interaction.Colchicine is an alkaloid isolated from colchicum autumnale with anti-gout and anti-inflammatory activities. The exact mechanism of action by which colchicines exerts its effect has not been completely established. Colchicine binds to tubulin, thereby interfering with the polymerization of tubulin, interrupting microtubule dynamics, and disrupting mitosis. This leads to an inhibition of migration of leukocytes and other inflam- matory cells, thereby reducing the inflammatory response to deposited urate crystals. Colchicine may also interrupt the cycle of monosodium urate crystal deposition in joint tissues, thereby also preventing the resultant inflammatory response. Overall, colchicine decreases leuko- cyte chemotaxismigration and phagocytosis to inflamed areas, and inhibits the formation and release of a chemotactic glycoprotein that is produced during phagocytosis of uratecrystals.
View Complete Details
Ask Latest Price & Details
Guaifenesin

Guaifenesin
  • Min. Order (MOQ) 25 Kilogram
  • WHITE CRYSTALLINE POWDER WHITE CRYSTALLINE POWDER
guaifenesin is an expectorant that also has some muscle relaxing action. it is used in many cough preparations.guaifenesin is a glyceryl guaiacolate with expectorant effects. guaifenesin increases respiratory tract mucus secretions, acts as an irritant to gastric vagal receptors and recruits efferent parasym- pathetic reflexes that cause glandular exocytosis. this agent reduces the viscosity of mucus secretion by reducing adhesiveness and surface tension as well as increasing hydration of mucus.guaifenesin promotes the efficiency of the mucociliary mechanism important in removing accumulated secretions from the upper and lower airway.
View Complete Details
Ask Latest Price & Details
Indapamide

Indapamide
  • Min. Order (MOQ) 25 Kilogram
  • WHITE CRYSTALLINE SOLID POWDER WHITE CRYSTALLINE SOLID POWDER
Indapamide is a benzamide-sulfonamide-indole derived diuretic that functions by inhibiting sodium chloride symporters.Indapamide is an indole derivative of chlorosulphonamide and a sulfamyl diuretic with antihypertensive activity. Indapamide may interact directly with the subunits of delayed rectifierpotassium channels, thereby blocking both slow and rapid k+ (iks and ikr) currents through the channels. Through the homeostasis mechanism in balancing total ion concentration (ca++, na+), it reduces vascular hyperreactivity and peripheral and arterial vascular resistance, possibly by inhibiting transmembrane ionic influx, probably calcium ions, and stimulating prostaglandin e2 synthesis, thereby causing vasodilatation. Indapamide exerts its diuretic effect by inhibiting reabsorption of sodium and chloride, primarily as a result of action on the cortical diluting segment of the renal distal tubule, thereby promoting urinary excretion of water and electrolytes.
View Complete Details
Ask Latest Price & Details
Doxazosin Mesylate

Doxazosin Mesylate
  • Min. Order (MOQ) 25 Kilogram
  • WHITE CRYSTALLINE POWDER WHITE CRYSTALLINE POWDER
Doxazosin mesylate is a prazosin-related compound that is a selective alpha-1-adrenergic blocker.Doxazosin mesylate is the mesylate salt form of doxazosin, a quinazoline compound with smooth muscle relaxing activity. Doxazosin mesylate selectively antagonizes alpha-1-adrenergic receptors in smooth muscle of the bladder neck and prostate, thereby relaxing the smooth muscle and decreasing the obstruction and urethral resistance seen with benign prostate hyperplasia (bph). This may improve bph symptoms. This agent also blocks alpha-1-adrenergic receptors in peripheral vascular smooth muscle, which leads to vasodilatation and a subsequent decrease in peripheral vascular resistance.
View Complete Details
Ask Latest Price & Details
pentoxifylline

Pentoxifylline
  • Min. Order (MOQ) 25 Kilogram
  • WHITE TO OFF-WHITE SOLID POWDER WHITE TO OFF-WHITE SOLID POWDER
Pentoxifylline is a methylxanthine derivative with hemorrheologic & immunomodulating properties. Pentoxifylline inhibits phosphodiesterase, resulting in increased levels of cyclic adenosine monophosphate (camp) in erythrocytes, endothelium & the surrounding tissues. This leads to vasodilation, improves erythrocyte flexibility & enhances blood flow. In addition the increased level of camp in platelets inhibits platelet aggre- gation which may contribute to a reduction in blood viscosity. This agent also inhibits production of tumor necrosis factor-alpha & inter- feron-gamma while it induces th2-like (t-helper 2) cytokine production, thereby inhibiting th1-mediated (t-helper 1) inflammatory & autoimmune responses.Pentoxifylline is a blood viscosity reducer. The physiologic effect of it is by means of hematologic activity alteration. Threfore, methy lxanthine derivative that inhibits phosphodiesterase & affects blood rheology. It improves blood flow by increasing erythrocyte & leukocyte flexibility. It also inhibits platelet aggregation. Pentoxi fylline modulates immunologic activity by stimulating cytokine production.
View Complete Details
Ask Latest Price & Details
Simvastatin

Simvastatin
  • Min. Order (MOQ) 25 Kilogram
  • WHITE SOLID POWDER WHITE SOLID POWDER
Simvastatin is a derivative of lovastatin and potent competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme a reductase (hydroxy methylglutaryl coa reductases), which is the rate-limiting enzyme in cholesterol biosynthesis. It may also interfere with steroid hormone production. Due to the induction of hepatic ldl receptors, it increases breakdown of ldl cholesterol. Simvastatin is a hmg-coa reductase inhibitor. The mechanism of action of simvastatin is as a hydroxy methylglutaryl-coa reductase inhibitor.Simvastatin is a lipid-lowering agent derived synthetically from a fermentation product of the fungus aspergillus terreus. Hydrolyzed in vivo to an active metabolite, simvastatincompetitively inhibits hepatic hydroxymethyl-glutaryl coenzyme a (hmg-coa) reductase, the enzyme which catalyzes the conversion of hmg-coa to mevalonate, a key step incholesterol synthesis. This agent lowers plasma cholesterol and lipoprotein levels, and modulates immune responses by suppressing mhc ii (major histocompatibility complex ii) on interferon gamma-stimulated, antigen-presenting cells such as human vascular endothelial cells.
View Complete Details
Ask Latest Price & Details
Candesartan

Candesartan
  • Min. Order (MOQ) 25 Kilogram
  • COLOURLESS CRYSTALLINE SOLID POWDER COLOURLESS CRYSTALLINE SOLID POWDER
Candesartan is an angiotensin 2 receptor blocker. The mechanism of action of candesartan is as an angiotensin 2 receptor antagonist.Candesartan is a synthetic, benzimidazole-derived angiotensin ii receptor antagonist prodrug with antihypertensive activity. candesartan selectively competes with angiotensin ii for the binding of the angiotensin ii receptor subtype 1 (at1) in vascular smooth muscle, blocking angiotensin ii-mediated vasoconstriction and inducing vasodilatation. In addition, antagonism of at1 in the adrenal gland inhibits angiotensin ii-stimulated aldosterone synthesis and secretion by the adrenal cortex; sodium and water excretion increase, followed by a reduction in plasma volume and blood pressure.
View Complete Details
Ask Latest Price & Details
Tell Us What are you looking for? Will call you back

Contact Us