Syncronei Medical India Private Limited Bangalore, Karnataka

CardioCel® is a single-ply, bio-scaffold material that remains functional, durable and free from calcification. The bio-scaffold is used to repair congenital heart deformities and more complex heart defects, it is also used to reconstruct dysfunctional heart valves and valve leaflets. We hope that in the future, CardioCel® may also be used for the manufacture of replacement tissue heart valves. CardioCel - TheatreCardioCel® is not only durable, but its natural flexibility and elasticity makes it easier to handle and use. Due to its tensile strength it is suitable for use in pressured environments like valves. CardioCel® also actively facilitates host tissue regeneration post-implantation. Long-term clinical studies using CardioCel® have shown no (or minimal) calcification seven years post-implantation, with strong ingrowth of normal heart tissue around the scaffold and blood-flow through and around the implant. CardioCel® is available at leading heart centres around the world and has the potential for use across a wide range of clinical applications.

Osteopore OsteoStrip provides a durable, biodegradable method of filling the void following a craniotomy. It provides rapid and homogenous vascularization after the procedure and ultimately results in high structural integrity and long-term integration with the surrounding bone. The naturally osteoconductive and bioresorbable OsteoStrip promotes bone formation due to its inter-connected and porous architecture. The FDA cleared OsteoStrip will ultimately result in high-strength bone growth to fill the void between the cranial flap and the cranium without the need for fixation through screws or other means - Key Benefits FDA-cleared for craniofacial indications Easy handling with no need for fixation Excellent biocompatibility Promotes bone formation Indications The OsteoStrip is indicated for use as a void filler between the cranial flap and surrounding cranium after a craniotomy procedure. Features FDA approved for craniofacial procedures Bioresorbable Osteoconductive

surgical staff is utilizing a revolutionary new skin closure modality for primary surgical incisions - INSORB® Absorbable Skin Staples. INSORB Staples are placed entirely underneath the skin in a rapid manner and offer many clinical advantages. Clinical evidence suggests that INSORB Absorbable Staples are low maintenance wounds and may result in fewer wound complications, including Surgical Site Infections.

The unique Syncrone INSORB Absorbable Skin Stapling Technology is a revolutionary new skin closure technology that places an absorbable staple entirely underneath the skin to close surgical incisions. Patients and clinicians now have a more comfortable, convenient and cosmetic choice for rapid skin closure. This unique device has won several national awards, including the 2006 Wall Street Journal Technology Innovation of the Year Award for medical devices. Incisive Surgical is the only company in the world that offers this technology and has sold over 1, 000, 000 Syncronei INSORB Absorbable Skin Staplers since the product launch in January 2005.