Zonisamide

We are offering zonisamide.
Zonisamide is an anti-epileptic agent. The mechanism action of zonisamide is as a carbonic anhydrase inhibitor & p-glycoprotein inhibitor. The physiologic effect ofzonisamide is by means of decreased central nervous system disorganized electrical activity. The chemical classi- fication of zonisamide is sulfonamides.
Zonisamide is a sulfonamide derivative with an anticonvulsant property the exact mechanism of action remains to be elucidated. zonisamide appears to block sodium & calciumchannels, thereby stabilizing neuronal membranes and suppressing neuronal hyper-synchronization. Although zonisamide shows affinity for the gamma-aminobutyric acid (gaba)benzodiazepine receptor ionophore complex, it does not potentiate the synaptic activity of gaba. In addition, this agent also facilitates both dopaminergic and serotonergic neurotransmission.
synonyms: (1, 2-benzoxazol-3-ylmethanesulfonamide
cas number: 68291-97-4, mol. Formula: c8h8n2o3s, mol.weight: 212.23
zonisamide is an off-white solid powder. It is soluble in water (10 mm), dmso (100 mm), 1.1eq naoh (100 mm), ethanol (25 mm), methanol, and ethyl acetate with melting range of 162°c to 167°c.
standard: offered of pharmaceutical grade bpuspep
packing: offered in export worthy packing of 25 kilos or as per our customer requirements