Methyl analog of dextrorphan that shows high affinity binding to several regions of the brain, including the medullary cough center.this compound is an nmda receptor antagonist (receptors, n-methyl-d-aspartate) and acts as a non-competitive channel blocker. Dextromethorphan hydrobromide is one of the widely used antitussives, and is also used to study the involvement of glutamate receptors in neurotoxicity.