Listing ID #7080360
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Chemically Gemcitabine is a Nucleoside Analog, in which the hydrogen atoms on the 2 carbons of Deoxycytidine are replaced by Fluorine atoms. As with Fluorouracil and other Analogues of Pyrimidines, the Triphosphates analogue of Gemcitabine replaces one of the building blocks of nucleic acids, in this case Cytidine. The process arrests growth, as new nucleosides can’t be attached to the “faulty” nucleoside. Resulting in Apoptosis. Another target of Gemcitabine is the enzyme Ribonucle otidereductase (RNR). The diphosphate analogue binds RNR active site and deactivates the enzyme irreversible. Once RNR is inhibited, the cell can’t produce the Deoxyribonucleotides required for DNA replication and and cell apoptosis is induced.
Indications:
Gemcitabine is used in various carcinomas: non-small cell Lung cancer, Pancreatic cancer, Bladder cancer and Breast cancer. It is being in vestigated for use in Oesophageal cancer and is used experimentally in Lymphomas and various other Tumor types.
Administration: Gemcitabine is administered by the IV route since it is extensively metabolized by the Gastro intestinal tract.
Dose ranges from 1-1.2mg/m2 according to the type of cancer treated.
Alish Life Saving Impex Pvt. Ltd was established in the year 2008 in Delhi, India. We are a manufacturer and supplier of radio shield protection lotion, pharmaceutical injection, Alish mouth spray and a lot more.
The company sees huge potential in Anti-Cancer drugs, post-radiation skin care treatment drugs, and Gastro and Nephro drugs. Most of the drugs are being presently imported and hence they are expensive and price prohibitive for Indian markets.
There is an immense scope for manufacturing of these branded drugs (under license) in India to make them more acceptable and affordable for the masses. Malnutrition is one of the major health issues in India. There is a huge demand for food supplements and High-protein food items. These Food supplements are known to be a great support to daily food and diet.
Our Infrastructure
Our modern-day infrastructure is well integrated with up-to-date R&D functions and manufacturing facilities. Sprawling across a large area, our company premises are divided into fully equipped divisions for manufacturing, stocking, packaging, and distribution.
Owing to the finesse of technological advancements, we have become able to streamline the stages of procuring, production and execution with utmost efficiency.
Our Strengths
Nature of Business
Manufacturer / Exporter / Supplier
Number of Employees
50 - 100
Year of Establishment
2008
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