Tranexamic Acid

We offer highly effective Tranexamic Acid Injection under the brand name of Transys. Transys is a haemostatic/ Antihaemorrhagic agent, contains Tranexamic Acid lOO mg/ml. It is available in the market in a clear 5ml Ampoule containing Tranexamic Acid 500mg /5ml. Today, we are counted among the prime Injectable Tranexamic Acid Exporters based in India.
Cunical Information
Cyklokapron Tranexamic Acid Injection, an antifibrinolytic agent, is used in the treatment of severe hemorrhage associated with excessive fibrinolysis (A process of breaking down of Fibrin Clot). Transys is used in the treatment of hemorrhage associated with severe Trauma of major surgical procedures such as thoracic surgery, in obstetric complications, in various neoplastic diseases such as metastatic carcinoma of the prostrate and leukemia and in hepatic cirrhosis.
Mode of Action
Transis acts by inhibiting plasminogen activators, which have fibrinolytic properties. .
Tranexamic acid competitively inhibits activation of plasminogen, thereby reducing conversion of plasminogen to plasmin (fibrinolysin), an enzyme that degrades fibrin clots, fibrinogen, and other plasma proteins, including the procoagulant factors V and VIII. Tranexamic acid also directly inhibits plasmin activity, but higher doses are required than are needed to reduce plasmin formation. In vitro, the antifibrinolytic potency of tranexamic acid is approximately 5 to 10 times that of aminocaproic acid
Dosage and Mode of Administration
Usual adult and adolescent dose 
Adults
Transys is administered by slow I.V. Injection in doses of 1 to 2 grams as per 15-30 mg/Kg Body Weight T.I.D or by 10 mg/Kg/Hour by Continuous Infusion. Transis injection should be administered intravenously at a rate not to exceed 100 mg (1 mL) per minute, to avoid inducing hypotension.
In hemophilia 1 - 1.5gm is given every 8 hours in the management of dental extractions.
Children
10mg/Kg BID or TID
Contraindications & Special Precautions
Tranexamic Acid should be administered with great caution in
Severe Renal failure, active intravascular clotting, thromboembolic disease, colour vision disorders.
Patients with massive haematuria from upper urinary tract.
Patients with irregular menstrual bleeding.
Pregnancy and lactation
Side Effects
Gastrointestinal disturbances, dizziness, colour and hypotension may occur after rapid IV Injection vision.