Listing ID #4206659
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Contact SupplierTopotecan Injection 2.5 & 4.5 mg is used in metastatic carcinoma of the ovary after failure of initial or subsequent chemo therapy and in small cell lung cancer disease after failure of first line chemotherapy. It is also used in combination therapy with cisplatin for Stage IV-B, recurrent, or persistent carcinoma of the cervix which is not amenable to curative treatment with surgery and/or radiation therapy. (1)
There are many generic manufacturers in India who manufacture Topotecan Injection 2.5 & 4.5 mg including Health Biotech Limited etc.
3s corporation is Supplier,Exporter ,Wholesaler for Topotecan Injection 2.5 & 4.5 mg in India.
ADDITIONAL INFORMATION
The recommended starting dose is 1.5mg/m2 body surface area by IV infusion over 30 minutes daily for 5 consecutive days In absence of tumor progression, a minimum of four courses are recommended, as tumour response may be delayed.
SIDE EFFECTS
• The most common hematologic side effects include:
neutropenia (97%), leukopenia (97%), anemia (89%), and thrombocytopenia (69%).
• The most common (>25%) non-hematologic side effects include:
nausea, alopecia, vomiting, sepsis or pyrexia/infection with neutropenia, diarrhea, constipation, fatigue, and pyrexia.
• The most common hematologic side effects include:
anemia (94%), leukopenia (91%), neutropenia (89%), and thrombocytopenia (74%).
• The most common (>25%) non-hematologic side effects include:
pain, nausea, vomiting, and infection/febrile neutropenia.