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Contact SupplierSumatriptan Is A Serotonin Agonist That Acts Selectively At 5ht1 Receptors. It Is Used In The Treatment Of Migraine Disorders. Sumatriptan Is A Serotonin-1b And Serotonin-1d Receptor Agonist. The Mechanism Of Action Of Sumatriptan Is As A Serotonin 1b Receptor Agonist & Serotonin 1d Receptor Agonist.
Sumatriptan Is A Sulfonamide Triptan With Vasoconstrictor Activity. Sumatriptan Selectively Binds To & Activates Serotonin 5-Ht1d Receptors In The Central Nervous System (CNS), Thereby Constricting Cerebral Blood Vessels. This May Lead To A Relief In Pain From Vascular Headaches. Sumatriptan May Also Relieve Vascular Headaches By Decreasing The Release Of Vasoactive Neuropeptides From Perivascular Trigeminal Axons In The Dura Mater During A Migraine, By Reducing Extravasation Of Plasma Proteins, And By Decreasing The Release Of Other Mediators Of Inflammation From The Trigeminal Nerve.
Sumatriptan Is A White Crystalline Solid Or Powder. It Is Soluble In water, 2.14x10+4 Mg/L At 25 Deg C (EST) With Melting Range Of 169°C TO 171°C.