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Sertaconazole is a topical antifungal agent used in the treatment of interdigital tinea pedis in immunocompetent patients. Sertaconazole nitrate is an antifungal medication of the imidazole class. It is available in topical formulations for the treatment of skin infections such as athlete's foot.Sertaconazole is used to treat tinea pedis (athlete's foot; fungal infection of the skin on the feet and between the toes). Sertaconazole is in a class of medications called imidazoles. It works by slowing the growth of fungi that cause infection.