Selegiline hydrochloride

Listing ID #1709037

We are offering selegiline hydrochloride.
Selegiline hydrochloride is a selective, irreversible inhibitor of type b monoamine oxidase. It is used in newly diagnosed patients with parkinson's disease. It may slow progression of the clinical disease and delay the requirement for levodopa therapy. It also may be given with levodopa upon onset of disability.
Selegiline hydrochloride is the hydrochloride salt form of selegiline, a levorotatory acetylenic derivative of phenethylamine with antiparkin sonian effect. As a selective monoamine oxidase (mao) inhibitor, selegiline has the greatest affinity for type b mao, found mainly in the brain. selegiline is converted by mao b to an active moiety, which binds irreversibly at the active site of the enzyme's cofactor fad (flavin adenine dinucleotide) molecule. This prevents the oxidative deamination of catecholamines and serotonin by mao b, and leads to an increase in these neurotransmitters' activities resulting in improved motor function. In addition, this agent may inhibit re-uptake of dopamine by the neuron and prolongdopamine activity.
synonyms: (2r)-n-methyl-1-phenyl-n-prop-2-ynylpropan-2-amine; hydrochloride
cas number: 14611-52-0, mol. Formula: c13h18cln, mol.weight: 223.74
selegiline is a crystalline solid. It is soluble in water (25 mgml), chloroform, ethanol, and methanol with melting range of 141.5°c tp 142.5°c.
standard: offered of pharmaceutical grade bpuspep
packing: offered in export worthy packing of 25 kilos or as per our customer requirements