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Contact SupplierWe are offering ramipril is a long-acting angiotensin-converting enzyme inhibitor. It is a prodrug that is transformed in the liver to its active metabolite ramiprilat. Ramipril is an angiotensin converting enzyme inhibitor. The mechanism of action of ramipril is as an angiotensin-converting enzyme inhibitor.
Ramipril is a prodrug and nonsulfhydryl angiotensin converting enzyme (ace) inhibitor with antihypertensive activity. Ramipril is converted in the liver by de-esterification into its active form ramiprilat, which inhibits ace, thereby blocking the conversion of angiotensin I to angiotensin ii. This abolishes the potent vasoconstrictive actions of angiotensin ii & leads to vasodilatation. This agent also causes an increase in bradykinin levels and a decrease in angiotensin ii-induced aldosterone secretion by the adrenal cortex, thereby promoting diuresis and natriuresis.
synonyms: (2s,3as,6as)-1-[(2s)-2-[[(2s)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-3,3a,4,5,6,6a-hexahydro-2h-cyclopenta[b]pyrrole-2-carboxylic acid
cas number: 87333-19-5, mol. Formula: c23h32n2o5, mol.weight: 416.51
ramipril is a white solid powder. It is soluble in water (