Listing ID #819448
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Propylene Glycol (IP/ USP), also called 1,2-propanediol or propane-1,2-diol, is an organic compound (a diol or double alcohol) with formula C3H8O2. It is a colorless, nearly odorless, clear, viscous liquid with a faintly sweet taste, hygroscopic and miscible with water, acetone, and chloroform.
Propylene Glycol finds its application in food and beverage, feed, cosmetics and pharmaceutical applications. Propylene Glycol USP/EP (pharmaceutical grade) is also used to dissolve flavoring in drinks, to keep animal feed moist, to homogeneously emulsify oily and watery elements in creams, sprays and liquids, or as solvent (excipient) for the active ingredients in medicines.
Pharmaceutical applications include :
| Test | Requrement |
|---|---|
| Description | A clear, colourless, viscous liquid ; practically odourless ; hygroscopic |
| Solubility | Miscible with water, with ethanol (95%) with acetone and with chloroform. |
| Identification | A) A violet colour slowly appears. B) A pleasant odour develops. C) No sharp, acrid smell of acrolein is perceptible. |
| Appearance of solution | Substance is clear and colourless. |
| Acidity | NMT 0.05ml of 0.1M NaOH is required. |
| Boiling Range | Between 184 º and 189 ºC |
| Relative Density | Between 1.035 and 1.040 |
| Refractive index | Between 1.431 and 1.433 |
| Heavy metals | NMT 5ppm |
| Oxidising Substances | Not more than 0.2 ml of 0.05M Sodium thiosuphate is required. |
| Reducing Substances | The solution does not changes is appearance within 5 minutes. |
| Ethylene glycol & diethylene glycol by GC. | No peaks corresponding ot Ethylene glycol & diethylene glycol are obtained in the chromatogram obtained with the test solution. |
| Sulphated ash | Not more than 0.01 Per cent w/w |
| Water | Not more than 0.2 per cent w/w |
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