Technical Specification It is ideal for shearing chromatin or DNA from small or large sample sizes for use in chromatin immunoprecipitation (ChIP), DNA methylation studies and Next-Gen sequencing. It can also be used for standard cell disruption, RNA shearing and other homogenization applications. EpiShear is backed by a two-year warranty and is supplied with an ultrasonic electric generator, a piezoelectric converter, a 1/8" microtip probe, converter & power cables, wrench set, and a comprehensive manual.