Pindolol is a moderately lipophilic beta blocker (adrenergic beta-antagonists). It is non-cardioselective and has intrinsic sympathomimetic actions, but little membrane-stabilizing activity. A moderately lipophilic beta blocker (adrenergic beta-antagonists). It is non-cardioselective and has intrinsic sympathomimetic actions, but little membrane-stabilizing activity. Pindolol is a sr-1asr-1b antagonist with similar affinity for each subtype. Pindolol acts as a partial agonist at mouse and human β3-ar (β3-adrenoceptors). Pindolol is an inhibitor of β1-ar.