PACGET Injection

Paclitaxel is among the most versatile chemotherapeutic drug used for the treatment of cancer. It was arguably the most important discovery in cancer treatment when it was launched worldwide as ‘Taxol’ in mid-90s. Today, paclitaxel is the backbone of several chemotherapy regimens used for ovarian cancer, breast cancer and lung cancer besides many other malignant tumours. Standard pretreatment regimen with dexamethasone 10 mg (for doses < 100 mgm2) and 20 mg (for doses > 100 mgm2) I.V. (see Decmax) along with diphenhydramine 50 mg I.V. and an H2-receptor antagonist I.V. should be administered 30-60 minutes before treatment.