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Contact SupplierOrtho-xylene is used mostly to produce phthalic anhydride, an important intermediate that leads principally to various coatings and plastics. The least valued of the isomers is meta-xylene, but it has uses in the manufacture of coatings and plastics. Most o-xylene is produced by cracking petroleum, which affords a distribution of aromatic compounds, including xylene isomers. ... o-Xylene is largely used in the production of phthalic anhydride, which is a precursor to many materials, drugs, and other chemicals.