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Contact SupplierCupressus sempervirens is a tree that grows up to 30 m tall. The leaves are 0.5 to 1 mm, dark green and obtuse. The male cones are 4 to 8 mm, the female are 25 to 40 mm. They are elliptical-oblong (rarely globose), green when young and shining yellowish-gray when ripe, with 8 to 14 short and obtusely spiked scales. There are 8 to 20 seeds on each scale. Cupressus sempervirens, also known as the Mediterranean cypress or Italian cypress, is native to the eastern Mediterranean region, North America and subtropical Asia at higher altitudes. Literature survey regarding its pharmacology revealed that Cupressus sempervirens has antiseptic, aromatherapeutic, astringent, balsamic or anti-inflammatory, antispasmodic, astringent, antiseptic, deodorant and diuretic activities. Literature survey regarding chemistry showed that monoterpenes, diterpenes, flavonoid glycoside and biflavonoid compounds are found in this species. The present review aims to highlight the chemistry, traditional uses and biological activities of the Cupressus sempervirens plant.