It has been estimated that from 15% to over 40% of patients taking Oral NSAIDs experience upper gastrointestinal symptoms, higher concentrations of NSAIDs are delivered to the desire site (e.g: Up to 100 times higher NSAIDs occurs in synovial fluid compared to that from NSAID blood level, Additions of Oleum lini, Menthol and Methylsalicylate offers effective counter irritant properties, increase blood supply at the site of application, Low blood levels of the drug reduce the incidence of drug interactions with low skin irritation at the application site.