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Contact SupplierWe are engaged in offering highly efficient Mecobalamin Injection in the national as well as international market. The Mecobalamin Intravenous Injection offered by us is especially formulated by our team of experts. Superior quality raw materials are used for producing Mecobalamin Injection. In addition to this, We are considered as one of the major Methylcobalamin Injection manufacturers based in India.
Composition (Each 2ml) :Indication & Dosage : Peripheral Neuropathies adult: 1500 MCG/day in 3 divided doses.Parenteral Peripheral Neuropathies adult: 500 MCG daily IM/IV 3 times/Wk.Parenteral Megaloblastic Anaemia caused by vitamin B12 deficiency adult: 500 MCG daily IM/IV 3 times/Wk. Maintenance Dose: After about 2 MTH of therapy, reduce dose to single admin of 500 MCG every 1-3 MTH. Administration : May be taken with or without food. Adverse Drug Reactions : Oral: Anorexia, Nausea, Vomiting and Diarrhoea. Parenteral: Rash, Headache, Hot Sensation, Diaphoresis and Pain/induration At IM INJ site. Potentially Fatal: Anaphylactoid Reactions (parenteral). Drug Interactions : Decreased GI Tract Absorption with Neomycin, Aminosalicylic Acid, H2-blockers and Colchicine. Reduced Serum Concentrations with Oral Contraceptives. Reduced Effects in Anaemia with Parenteral Chloramphenicol. Lab Interference :May interfere with Precise Diagnosis in Patients with Folate Deficiency. Storage : Oral: Store At room temperature. Protect from moisture and light. Parenteral: store at room temperature. Do not expose to direct light. Mechanism of Action : Mecobalamin is the Neurologically Active form of vitamin B12 and occurs as a water-soluble vitamin in the body. It is a cofactor in the Enzyme Methionine Synthase, Which functions to transfer Methyl groups for the regeneration of Methionine from Homocysteine. In Anaemia, it increases Erythrocyte production by promoting Nucleic Acid Synthesis in the bone marrow and by promoting maturation and division of Erythrocytes. Absorption: Peak Plasma concentrations after 3 Hr (oral); 0.9 Hr (IM); 3 Min (IV). Excretion: Via Urine.