Levocetirizine Dihydrochloride

Listing ID #3169004

Levocetirizine dihydrochloride is the dihydrochloride salt form of the active levorotatory enantiomer of cetirizine, levocetirizine; a third generation, non-sedating, selective histamineh1 receptor antagonist, with antihistamine, anti-inflammatory and potential anti-angiogenic activities. Levocetirizine competes with endogenous histamine for binding at peripheral h1-receptor sites on the effector cell surface. This prevents the negative symptoms associated with histamine release & an allergic reaction. In addition, as histamine plays an important role in angiogenesis during an allergic inflammatory reaction, blocking the action of histamine may modulate the expression of proangiogenic factors and thus may prevent angiogenesis. As a third-generation histamine h1 receptor antagonist, levocetirizine has fewer side effects than most second-generation antihistamines.