Irinotecan is an antineoplastic enzyme inhibitor primarily used in the treatment of colorectal cancer. It is a derivative of camptothecin that inhibits the action of topoisomerase i.irinotecan prevents religation of the dna strand by binding to topoisomerase i-dna complex, and causes double-strand dna breakage and cell death. It is a derivative of camptothecin. Irinotecan was approved for the treatment of advanced pancreatic cancer in october, 2015 (irinotecan liposome injection, trade name onivyde).

Irinotecan is an antineoplastic enzyme inhibitor primarily used in the treatment of colorectal cancer. It is a derivative of camptothecin that inhibits the action of topoisomerase i.irinotecan prevents religation of the dna strand by binding to topoisomerase i-dna complex, and causes double-strand dna breakage and cell death. It is a derivative of camptothecin. Irinotecan was approved for the treatment of advanced pancreatic cancer in october, 2015 (irinotecan liposome injection, trade name onivyde).