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Contact Supplierwe are leading manufacturer and exporter of pharmaceutical raw material hydrochlorothiazide (hctz or hct) is a diuretic medication often used to treat high blood pressure and swelling due to fluid build up. Other uses include diabetes insipidus, renal tubular acidosis, and to decrease the risk of kidney stones in those with a high calcium level in the urine. For high blood pressure it is sometimes considered as a first-line treatment, although chlorthalidone is more effective with a similar rate of adverse effects. Hctz is taken by mouth and may be combined with other blood pressure medications as a single pill to increase effectiveness.