CEFVAC-B (Hepatitis – B Vaccine (rDNA) I.P.) is a non-infectious recombinant DNA Hepatitis B Vaccine. It contains purified surface antigen of the virus obtained by culturing genetically engineered Hansenula polymorpha yeast cells having the surface antigen gene of the Hepatitis B virus. It is indicated for active immunisation against hepatitis B infection in subjects considered at risk of exposure to HBV-positive material.