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**Glimepiride 1 mg + Metformin 500 mg + Pioglitazone 15 mg Tablets**
This combination tablet contains three antidiabetic agents—Glimepiride, Metformin, and Pioglitazone—used to manage blood sugar levels in individuals with type 2 diabetes mellitus.
1. **Glimepiride (1 mg)**: A sulfonylurea that helps lower blood sugar by increasing the release of insulin from the pancreas.
2. **Metformin (500 mg)**: A biguanide that reduces glucose production in the liver and improves the body's sensitivity to insulin, helping to control blood sugar levels.
3. **Pioglitazone (15 mg)**: A thiazolidinedione that enhances insulin sensitivity in muscle and adipose tissue, making it easier for cells to absorb glucose from the bloodstream.
This combination works synergistically to help patients achieve better glycemic control, especially when diet, exercise, or monotherapy is insufficient. It is typically prescribed under medical supervision for the treatment of type 2 diabetes.
**Uses**:
- Type 2 diabetes management
**Dosage**:
Take as directed by a healthcare provider, usually once daily with meals to reduce gastrointestinal side effects.
**Precautions**:
- Regular monitoring of blood sugar levels is recommended.
- Inform your healthcare provider about any history of heart disease, liver problems, or kidney disease.
- This combination may increase the risk of hypoglycemia (low blood sugar) and may not be suitable for all patients.
**Side Effects**:
- Hypoglycemia
- Gastrointestinal discomfort (e.g., nausea, diarrhea)
- Weight gain
- Edema (swelling)
Consult a healthcare professional for personalized advice.