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Fluphenazine is an antipsychotic medication used to treat schizophrenia and psychotic symptoms such as hallucinations, delusions, and hostility. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.Fluphenazine is a phenothiazine used to treat patients requiring long-term neuroleptic therapy. A phenothiazine used in the treatment of psychoses. Its properties and uses are generally similar to those of chlorpromazine.