Disopyramide Phosphate

We are offering disopyramide phosphate is a class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholin- ergic and local anesthetic properties.
Disopyramide phosphate is a class ia antiarrhythmic agent with cardiac depressant properties. Disopyramide phosphate exerts its actions by blocking both sodium and potassiumchannels in cardiac membrane during phase 0 of the action potential. This slows the impulse conduction through the av node and prolongs the duration of the action potential of normal cardiac cells in atrial and ventricular tissues. disopyramide prolongs the qt interval and causes a widening of the qrs complex. It also possesses some anticholinergic and local anaesthetic properties. Disopyramide phosphate is used in the treatment of supraventricular tachycardia.
synonyms: 4-[di (propan-2-yl) amino]-2-phenyl-2-pyridin-2-ylbutanamide; phosphoric acid
cas number: 22059-60-5, mol. Formula: c21h32n3o5p, mol.weight: 437.47
disopyramide phosphate is in solid form. It is freely soluble in water, and the free base (pka 10.4) has an aqueous solubility of 1 mgml with melting point of 94°c.
Standard: offered of pharmaceutical grade bpuspep
packing: offered in export worthy packing of 25 kilos or as per our customer requirements