Cytarabine Hydrochloride

Listing ID #1707700

We are offering cytarabine hydrochloride.
Cytarabine hydrochloride is a pyrimidine nucleoside analog that is used mainly in the treatment of leukemia, especially acute non-lymphoblastic leukemia. Cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of dna. Its actions are specific for the s phase of the cell cycle. It also has antiviral and immunosuppressant properties.
Cytarabine hydrochloride is the hydrochloride form of cytarabine, an antimetabolite analogue of cytidine with a modified sugar moiety (arabinose instead of ribose). Cytarabine is converted to the tri- phosphate form within the cell and then competes with cytidine for incorporation into dna. Because the arabinose sugar sterically hinders the rotation of the molecule within dna, dna replication ceases, specifically during the s phase of the cell cycle. This agent also inhibits dna polymerase, resulting in a decrease in dna replication and repair.
synonyms: 4-amino-1-[(2r, 3s, 4s, 5r)-3, 4-dihydroxy-5-(hydroxymethyl) oxolan-2-yl] pyrimidin-2-one; hydrochloride
cas number: 69-74-9, mol. Formula: c9h14cln3o5, mol.weight: 279.68
cytarabine is a white to off-white crystalline powder. It is soluble in water (50 mgml) with melting range of 197°c to 198°c.
Standard: offered of pharmaceutical grade bpuspep
packing: offered in export worthy packing of 25 kilos or as per our customer requirements