Curcumin is the major yellow pigment of turmeric, a commonly used spice, derived from the rhizome of the herb Curcuma longa Linn. In the Indian subcontinent and Southeast Asia, turmeric has traditionally been used for the treatment of inflammation, skin wounds, and tumors. Clinical activity of curcumin is yet to be confirmed. However, in preclinical animal models, curcumin has shown chemo preventive, anti-neoplastic and anti-inflammatory properties.