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Contact SupplierGuggul is the yellowish resin (or gum) that is produced by Commiphora mukul, a small, thorny plant that grows throughout northern India. Its active components, Z-guggulsterone and E-guggulsterone, have an ability to lower both cholesterol and triglyceride levels. Specifically, guggulipid lowers VLDL and LDL cholesterol and triglycerides while simultaneously raising HDL cholesterol.
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This indicates guggul's primary use for providing protection against atherosclerosis. These effects are due to guggul's action on the liver which is stimulated to metabolise LDL cholesterol, effectively lowering the amount in the bloodstream.
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Native to India, Guggul lipid has been used for a long time in Ayurvedic medicine to treat obesity and other weight related problems. Today, Guggul is frequently used to help lower cholesterol levels and decrease high blood pressure.
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In chemical composition guggulu (extracted resin) consist of octanordammarana terpenes manusumbionic acid and manusumbinone as obtained from chemical analysis.
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One of the main uses of Guggul is treatment of high cholesterol. Gum Guggul both lowered cholesterol levels and also separately protected against the development of hardening of the arteries. Guggul can improve cholesterol levels. Gum Guggul is said to help reduce high cholesterol, because it lowers harmful low-density lipoproteins while elevating the beneficial high-density lipoproteins.
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Guggul may lower serum cholesterol levels by as much as 24%, and triglyceride levels by as much as 23%, by increasing the hepatic binding of LDL cholesterol. Its effects on HDL cholesterol levels are variable, either increasing or decreasing.
The guggulsterone, the active ingredient in the guggul extract, blocks the activity of a receptor in the liver's cells called Farnesoid X Receptor (FXR). Guggul blocks the receptor and affects how cholesterol is metabolised.
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Botanical Name |
: | Commiphora mukul |
Common Name | : | Guggul, Guggulu, Guggulow |
Family Name | : | Burseraceae (frankincense) |
Plant Part Used | : | Oleo-gum resin of whole plant habit |
Description | : | Off white to light yellow |
Application | : | |
Active Principle | : | The primary chemical constituents of Guggul include phytosterols, guggulipids & guggulsterones. |