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Clarithromycin is a semisynthetic macrolide antibiotic derived from erythromycin that is active against a variety of microorganisms. It can inhibit protein synthesis in bacteria by reversibly binding to the 50s ribosomal subunits. This inhibits the translocation of aminoacyl trans- fer-rna and prevents peptide chain elongation. Clarithromycin is a macrolide antimicrobial.the mechanism of action of clarithromycin is as a cytochrome p450 3a4 inhibitor, cytochrome p450 3a inhibitor, and p-gly coprotein inhibitor. The chemical classification of clarithromycin is macrolides.
Clarithromycin is a semisynthetic 14-membered ring macrolide antibiotic. Clarithromycin binds to the 50s ribosomal subunit and inhibits rna-dependent protein synthesis in susceptible organisms. Clarith romy- cin has been shown to eradicate gastric malt (mucosa-associated lymphoid tissue) lymphomas, presumably due to the eradication of tumorigenic helicobacter pylori infection. This agent also acts as a biological response modulator, possibly inhibiting angiogenesis and tumor growth through alterations in growth factor expression
synonyms: (3r,4s,5s,6r,7r,9r,11r,12r,13s,14r)-6-[(2s,3r,4s,6r)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-12,13-dihydroxy-4-[(2r,4r,5s,6s)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-7-methoxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione
cas number: 81103-11-9, mol. Formula: c38h69no13, mol.weight: 747.95
clarithromycin is a colourless crystalline needles powder. It is soluble in ethanol (