CELKERAN(CHLORAMBUCIL)

• chemotherapy drug
• nitrogen mustard alkylating agent
• immunosuppressive drug

 

 

Chlorambucil is a chemotherapy drug that has been mainly used in the treatment of chronic lymphocytic leukemia. It is a nitrogen mustard alkylating agent . It also has been used as an immunosuppressive drug for various autoimmune and inflammatory conditions, such as nephrotic syndrome. In India, its manufactured by two companies Natco & Celon. Celon sells it on the brand name of Celkeran 2 mg tablet. Packing is for 30 tabs per pack.

 

SIDE EFFECTS INCLUDE:   GI DISTURBANCES; HEPATOTOXICITY; SKIN RASHES; PERIPHERAL NEUROPATHY; CENTRAL NEUROTOXICITY INCLUDING SEIZURES; INTERSTITIAL PNEUMONIA, PULMONARY FIBROSIS. HIGH DOSES MAY PRODUCE AZOOSPERMIA AND AMENORRHOEA. STERILITY WHEN GIVEN TO BOYS AT OR BEFORE PUBERTY. POTENTIALLY FATAL: SEVERE BONE MARROW SUPPRESSION, CARCINOGENIC AND HUMAN INFERTILITY.