Tamarind kernel powder is a rich source of xyloglucan gum and carboxymethylation of tamarind kernel powder is carried out mainly with a view to utilize the tamarind gum for broader applications. When Carboxymethylation is done to tamarind kernel powder it increases its solubility in cold water and the stability of its paste to microorganisms and the reaction conditions are optimized with respect to concentration of sodium hydroxide, monochloroacetic acid, solvent ratio, reaction time, and reaction temperature