Cantret Capsules

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What is Cantret (Altretamine)?

• Altretamine is a cancer (antineoplastic) medication. Altretamine interferes with the growth of cancer cells and slows their growth and spread in the body.
• Altretamine is used to treat cancer of the ovaries.
• Altretamine may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Cantret (altretamine)?

• Altretamine should only be administered under the supervision of a qualified healthcare provider experienced in the use of cancer chemotherapeutic agents.

Serious side effects have been reported with the use of altretamine including :

• allergic reactions (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); decreased bone marrow function and blood problems (extreme fatigue; easy bruising or bleeding; black, bloody or tarry stools; fever or chills; or signs of infection such as fever; chills, or sore throat); neurologic problems (mood disorders, altered consciousness, weakness, dizziness, vertigo); and others. Talk to your doctor about the possible side effects from treatment with altretamine.

What should I discuss with my healthcare provider before taking Cantret (altretamine)?

• Before taking altretamine, tell your doctor if you have :
• Any nervous system (brain and nerves) problems; or bone marrow problems.
• You may not be able to take altretamine, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.
• Altretamine is in the FDA pregnancy category D. This means that altretamine is known to cause birth defects in an unborn baby.
• Do not take altretamine without first talking to your doctor if you are pregnant or could become pregnant during treatment. Contraceptive measures are recommended during treatment with altretamine.
• It is not known whether altretamine passes into breast milk. Do not take altretamine without first talking to your doctor if you are breast feeding a baby.