Busulfan

We are offering busulfan.
An alkylating agent having a selective immunosuppressive effect on bone marrow it has been used in the palliative treatment of chronic myeloid leukemia (myeloid leukemia, chronic), but although symptomatic relief is provided, no permanent remission is brought about. According to the fourth annual report on carcinogens (ntp 85-002, 1985), busulfan is listed as a known carcinogen.
Busulfan is an alkylating drug. The mechanism of action of busulfan is as an alkylating activity.
Busulfan is a synthetic derivative of dimethane-sulfonate with antineoplastic and cytotoxic properties. Although its mechanism of action is not fully understood, busulfan appears to act through the alkylation of dna. Following systemic absorption of busulfan, carbonium ions are formed, resulting in dna alkylation and dna breaks and inhibition of dna replication and rna transcription.
synonyms: 4-methylsulfonyloxybutyl methanesulfonate
cas number: 55-98-1, mol. Formula: c6h14o6s2, mol.weight: 246.3
busulfan is a white needles powder. It is soluble in acetone, 100% ethanol or dmso; insoluble in water with melting range of 114°c to 117°c.
Standard: offered of pharmaceutical grade bpuspep
packing: offered in export worthy packing of 25 kilos or as per our customer requirements