. The Bromelain Study
The proposed study is an investigation into the treatment of knee pain using bromelain in otherwise healthy individuals.
3.1 Aims
To investigate the effects of bromelain on knee pain in an open study.
To compare different doses of bromelain on the response to treatment.
3.2 Recruitment
500 healthy men and women currently suffering from knee pain, will be recruited by articles in national newspapers, magazines and radio programs.
3.3 Exclusion Criteria
Subjects will be screened for exclusion criteria by their responses to the General Questionnaire (Appendix I). This questionnaire contains specific questions on current medication, as well as questions which screen for the presence of disease.
Specific exclusion criteria:
As this is a study in essentially healthy people, subjects with any serious medical disorder that requires treatment (medical or otherwise) for the normal functioning, well-being or life expectancy of the individual will be excluded
Volunteers on anticoagulant therapy will be specifically excluded
Volunteers currently using anti-inflammatory/analgesic drugs for knee pain will also be excluded

. The Bromelain Study
The proposed study is an investigation into the treatment of knee pain using bromelain in otherwise healthy individuals.
3.1 Aims
To investigate the effects of bromelain on knee pain in an open study.
To compare different doses of bromelain on the response to treatment.
3.2 Recruitment
500 healthy men and women currently suffering from knee pain, will be recruited by articles in national newspapers, magazines and radio programs.
3.3 Exclusion Criteria
Subjects will be screened for exclusion criteria by their responses to the General Questionnaire (Appendix I). This questionnaire contains specific questions on current medication, as well as questions which screen for the presence of disease.
Specific exclusion criteria:
As this is a study in essentially healthy people, subjects with any serious medical disorder that requires treatment (medical or otherwise) for the normal functioning, well-being or life expectancy of the individual will be excluded
Volunteers on anticoagulant therapy will be specifically excluded
Volunteers currently using anti-inflammatory/analgesic drugs for knee pain will also be excluded