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Contact SupplierOsteoarthritis : Boswellia serrata have been shown to be specific, nonredox and noncompetitive inhibitors of 5-lipoxygenase, the key enzyme of leukotriene biosynthesis.
Boswellic acids inhibit the 5-lipoxygenase pathway by which Arachadonic acid is converted to Leukotrienes. Boswellic acids do not appear to inhibit the other two enzymes, which metabolize Arachadonic acid, 12-lipoxygenase and cyclooxygenase.
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