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betamethasone sodium phosphate betamethasone sodium phosphate, usp is a strong glucocorticoid steroid and has anti-inflammatory and immunosuppressive properties. It has the added advantage of not causing water retention, unlike other potent drugs of this type. This item is formulated as a topical cream, ointment, lotion, gel or even foam and the sodium phosphate salt can be administered as an intramuscular injection.