Benazepril Hydrochloride

We are offering benazepril hydrochloride.
Benazepril hydrochloride is the hydrochloride salt of benazepril, a carboxyl-containing angiotensin-converting enzyme (ace) inhibitor with antihypertensive activity. As a prodrug,benazepril is metabolized to its active form benazeprilat. Benazeprilat competitively binds to and inhibits ace, thereby blocking the conversion of angiotensin I to angiotensin ii. This prevents the potent vasoconstrictive actions of angiotensin ii, resulting in vasodilation.
Benazeprilat also decreases angiotensin ii-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow. Benazepril is a prodrug which is metabolized by the liver into its active formbenazeprilat via cleavage of the drug's ester group.
synonyms: 2-[(3s)-3-[[(2s)-1-ethoxy-1-oxo-4-phenylbutan-2-yl] amino]-2-oxo-4, 5-dihydro-3h-1-benzazepin-1-yl] acetic acid; hydrochloride
cas number: 86541-74-4, mol. Formula: c24h29cln2o5, mol.weight: 460.95
benazepril hydrochloride is a white crystalline solid powder. It is soluble in water (50 mm), dmso (100 mm), ethanol, and methanol with melting range of 188°c to 190°c.
Standard: offered of pharmaceutical grade bpuspep
packing: offered in export worthy packing of 25 kilos or as per our customer requirements