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Aztreonam is a monocyclic beta-lactam antibiotic originally isolated from chromobacterium violaceum. It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges, bladder, and kidneys. It may cause a superinfection with gram-positive organisms. Aztreonam is a monobactam antibacterial. The chemical classification of aztreonam is monobactams.
Aztreonam is a monocyclic beta-lactam antibiotic originally isolated from chromobacterium violaceum with bactericidal activity. Aztreonam preferentially binds to and inactivatespenicillin-binding protein-3 (pbp-3), which is involved in bacterial cell wall synthesis, thereby inhibiting bacterial cell wall integrity and leading to cell lysis and death. This agent differs from other beta-lactam antibiotics because it is resistant to beta-lactamase hydrolysis, and it is usually used to treat infections caused by gram-negative aerobic microorganisms.
synonyms: 2-[(z)-[1-(2-amino-1,3-thiazol-4-yl)-2-[[(2s,3s)-2-methyl-4-oxo-1-sulfoazetidin-3-yl]amino]-2-oxoethylidene]amino]oxy-2-methylpropanoic acid
cas number: 78110-38-0 mol. Formula: c13h17n5o8s2, mol.weight: 435.43
aztreonam is a white crystalline powder. It is soluble in dimethylformamide, dimethyl sulfoxide and water with melting point of 227°c.
Standard: offered of pharmaceutical grade bpuspep
packing: offered in export worthy packing of 25 kilos or as per our customer requirements