Avastin is used frequently by ophthalmologists. Word search for avastin in the Indian Journal of Ophthalmology website produced 33 articles for the period between 2007 and January 2009, sign of the increased usage of the drug. The reduction of fluid in the retina and improvement in vision after avastin injection is gratifying to all concerned [Figures [Figures1 1 and and2]. 2]. Many with conflicting interests are claimants to this success. There are legal, financial, industrial and ethical implications and the ophthalmologist must be aware of these implications.