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Contact SupplierAtenolol is a beta blocker that works specifically on the heart. It works by slowing down the heart rate and makes the heart more efficient at pumping blood throughout the body. The exact mechanism by which Atenolol prevents migraines is not established yet and may vary from person to person. Atenolol can prevent migraines by decreasing the excitability of the nervous system. Atenolol is also believed to decrease the dilation of blood vessels that are responsible for migraine.