ASACOL 500MG

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uses:use in the elderly should be cautious and subject to patients having normal renal function.

renal disorder: mesalazine is excreted rapidly by the kidney, mainly as its metabolite, n-acetyl-5-aminosalicylic acid. in rats, large doses of mesalazine injected intravenously produce tubular and glomerular toxicity. asacol should be used with extreme caution in patients with confirmed mild to moderate renal impairment (see section 4.3). treatment with mesalazine should be discontinued if renal function deteriorates. if dehydration develops, normal electrolyte and fluid balance should be restored as soon as possible.

serious blood dyscrasias have been reported very rarely with mesalazine. haematological investigations should be performed if the patient develops unexplained bleeding, bruising, purpura, anaemia, fever or sore throat. treatment should be stopped if there is suspicion or evidence of blood dyscrasia.