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Contact SupplierAcetone is a liquid solvent that can break down and dissolve other substances. Companies include acetone in products such as nail polish remover, paint remover, and varnish remover. Some also use acetone to manufacture plastics, lacquers, and textiles. Acetone is a chemical used to make products like nail polish remover and paint remover. Your body also makes this chemical when it breaks down fat. Acetone is safe in normal amounts, but too much of it could be a problem.